(3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole

Base Information

Chemical Name:(3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole
CAS No.:40982-92-1
Molecular Formula:C₁₉H₂₆O₆
Molecular Weight:350.412
Hs Code.:

Synonyms:(3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole

Suppliers and Price of (3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole

There total 7 articles about (3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 100-39-0
benzyl bromide

: 286011-06-1
1,2:5,6-di-O-isopropylidene-α-D-galactofuranose

: 18685-18-2,22331-21-1,23885-38-3,40982-92-1,65451-98-1,101475-83-6,134275-38-0,145625-96-3
3-O-benzyl-1,2:5,6-di-O-isopropylidene-β-L-idofuranose

Guidance literature:: With sodium hydride; at 20 ℃;
DOI:10.1039/c004502k

Reference yield:

: 26597-74-0
1,2:5,6-di-O-isopropylidene-β-L-talofuranose

: 100-39-0
benzyl bromide

: 40982-92-1
(3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole

Guidance literature:: 1,2:5,6-di-O-isopropylidene-β-L-talofuranose; With sodium hydride; In acetonitrile; mineral oil; at 0 ℃; for 0.5h;

benzyl bromide; In acetonitrile; mineral oil; at 20 ℃; for 3h;

Reference yield:

: 22331-19-7
3-O-benzyl-1,2-O-isopropylidene-5,6-di-O-mesyl-α-D-glucofuranose

: 18685-18-2,22331-21-1,23885-38-3,40982-92-1,65451-98-1,101475-83-6,134275-38-0,145625-96-3
3-O-benzyl-1,2:5,6-di-O-isopropylidene-β-L-idofuranose

Guidance literature:: Multi-step reaction with 3 steps

1: dimethylformamide / 6 h / Heating

2: sodium methoxide / CH₂Cl₂; methanol / 2 h / Ambient temperature

3: camphorsulfonic acid / dimethylformamide / 1 h / Ambient temperature

With camphor-10-sulfonic acid; sodium methylate; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo00383a005