1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one

Base Information

• Chemical Name: 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one
• CAS No.: 146307-40-6
• Molecular Formula: C₂₈H₂₀O₃
• Molecular Weight: 404.465
• Mol file: 146307-40-6.mol

Synonyms:1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one

Chemical Property of 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one

There total 10 articles about 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.5%

1,1'-((4-methoxyphenyl)methylene)bis(naphthalen-2-ol) (66595-89-9) → 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one (146307-40-6)

Guidance literature:

With sodium hydrogencarbonate; In water; acetonitrile; at 40 ℃; for 21.88h; pH=8.3; Electrochemical reaction; aq. buffer;

DOI:10.1002/jhet.5570450516

Reference yield: 92.0%

1,1'-((4-methoxyphenyl)methylene)bis(naphthalen-2-ol) (66595-89-9) → 1'-(4-methoxyphenyl)-spiro{naphthalene-1(2H),2'(1'H)-naphtho[2,1-b]furan}-2-one (76048-53-8,76048-63-0,76115-35-0,76115-41-8,146307-40-6)

Guidance literature:

With trichloroisocyanuric acid; sodium hydrogencarbonate; In water; acetone; at 20 ℃; for 0.0833333h; diastereoselective reaction;

DOI:10.1002/jhet.5570450516

Reference yield: 83.0%

1,1'-((4-methoxyphenyl)methylene)bis(naphthalen-2-ol) (66595-89-9) → 1'-(4-methoxyphenyl)-spiro{naphthalene-1(2H),2'(1'H)-naphtho[2,1-b]furan}-2-one (76048-53-8,76048-63-0,76115-35-0,76115-41-8,146307-40-6)

Guidance literature:

With triphenylbismuthane; for 0.233333h; diastereoselective reaction; Microwave irradiation; neat (no solvent);

DOI:10.1002/jhet.5570450516

upstream raw materials:

Acetic acid 1-[(2-acetoxy-naphthalen-1-yl)-(3,4,5-trimethoxy-phenyl)-methyl]-naphthalen-2-yl ester

1,1'-((4-methoxyphenyl)methylene)bis(naphthalen-2-ol)

4-methoxy-benzaldehyde

β-naphthol

Downstream raw materials:

Methyl 2-(1'-(4-methoxyphenyl)-naphtho<2,1-b>pyrrol-2'-yl)-cinnamate

n-Propyl-2-(1'-(4-methoxyphenyl)-naphtho<2,1-b>pyrrol-2'-yl)cinnamate

Ethyl 2-(1'-(4-methoxyphenyl)-naphtho<2,1-b>pyrrol-2'-yl)cinnamate

Oxime of 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one