1-[(2-Hydroxy-1-naphthyl)(4-methoxyphenyl)methyl]-2-naphthol

Base Information

• Chemical Name: 1-[(2-Hydroxy-1-naphthyl)(4-methoxyphenyl)methyl]-2-naphthol
• CAS No.: 66595-89-9
• Molecular Formula: C28H22O3
• Molecular Weight: 406.481
• Hs Code.: 2909499000
• European Community (EC) Number: 666-234-6
• DSSTox Substance ID: DTXSID90379010
• Nikkaji Number: J1.497.100I
• Wikidata: Q82168661
• Mol file: 66595-89-9.mol

Synonyms:66595-89-9;1-[(2-hydroxy-1-naphthyl)(4-methoxyphenyl)methyl]-2-naphthol;1-[(2-hydroxynaphthalen-1-yl)-(4-methoxyphenyl)methyl]naphthalen-2-ol;1,1-p-Anisylidenebis(2-naphthol);1,1'-p-Anisylidene-bis-(2-naphthol);1,1'-BIS(2-HYDROXYNAPHTHYL)-4-METHOXYPHENYLMETHANE;DTXSID90379010;1-[(2-hydroxynaphthalen-1-yl)(4-methoxyphenyl)methyl]naphthalen-2-ol;AKOS015913269;FT-0606160;1,1'-(4-Methoxybenzylidene)bis(2-naphthol);1,1'-(4-METHOXYBENZYLIDENE)DI-2-NAPHTHOL;A835500;1,1'-((4-methoxyphenyl)methylene)dinaphthalen-2-ol;1,1'-[(4-Methoxyphenyl)methanediyl]bis-2-naphthol;1,1'-((4-Methoxyphenyl)methylene)bis(naphthalen-2-ol);1,1'-[(4-Methoxyphenyl)methylene]di(naphthalen-2-ol);6-(3-Chlorophenyl)-5,6-dihydroimidazo[2,1-b]thiazole;1-[(2-Hydroxy-1-naphthyl)(4-methoxyphenyl)methyl]-2naphthol;1-[(2-hydroxy-1-naphthalenyl)-(4-methoxyphenyl)methyl]-2-naphthalenol;1-[(4-methoxyphenyl)-(2-oxidanylnaphthalen-1-yl)methyl]naphthalen-2-ol

Chemical Property of 1-[(2-Hydroxy-1-naphthyl)(4-methoxyphenyl)methyl]-2-naphthol

Chemical Property:

• Melting Point: 184-185oC
• Boiling Point: 634.2oC at 760 mmHg
• Flash Point: 337.3oC
• PSA: 49.69000
• Density: 1.263g/cm3
• LogP: 6.59300
• XLogP3: 7.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 406.15689456
• Heavy Atom Count: 31
• Complexity: 533

Purity/Quality:

99% ^*data from raw suppliers

1,1'-BIS(2-HYDROXYNAPHTHYL)-4-METHOXYPHENYLMETHANE 95.00% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(C2=C(C=CC3=CC=CC=C32)O)C4=C(C=CC5=CC=CC=C54)O

Technology Process of 1-[(2-Hydroxy-1-naphthyl)(4-methoxyphenyl)methyl]-2-naphthol

There total 2 articles about 1-[(2-Hydroxy-1-naphthyl)(4-methoxyphenyl)methyl]-2-naphthol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-methoxy-benzaldehyde (123-11-5) + β-naphthol (135-19-3) → 1,1'-((4-methoxyphenyl)methylene)bis(naphthalen-2-ol) (66595-89-9)

Guidance literature:

With trifluorormethanesulfonic acid; In ethanol; at 60 ℃; for 24h; under 2250180 Torr;

DOI:10.1016/S0040-4039(01)00208-8

Reference yield:

4-methoxy-benzaldehyde (123-11-5) + acetic acid (64-19-7,77671-22-8) + β-naphthol (135-19-3) → 1,1'-((4-methoxyphenyl)methylene)bis(naphthalen-2-ol) (66595-89-9)

Guidance literature:

anschliessenden Versetzen mit konz. wss. Salzsaeure bei 5grad;

DOI:10.1021/jo01232a005

Reference yield: 94.5%

1,1'-((4-methoxyphenyl)methylene)bis(naphthalen-2-ol) (66595-89-9) → 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one (146307-40-6)

Guidance literature:

With sodium hydrogencarbonate; In water; acetonitrile; at 40 ℃; for 21.88h; pH=8.3; Electrochemical reaction; aq. buffer;

DOI:10.1002/jhet.5570450516

upstream raw materials:

4-methoxy-benzaldehyde

acetic acid

β-naphthol

Downstream raw materials:

bis-(2-methoxy-[1]naphthyl)-(4-methoxy-phenyl)-methane

1'-(4-methoxyphenyl)-spiro{naphthalene-1(2H),2'(1'H)-naphtho[2,1-b]furan}-2-one

14-(4'-methoxyphenyl)-14H-dibenzo[a,j]xanthene

1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one