2,5-diphenyl-4-acetoxythiazole

Base Information

Chemical Name:2,5-diphenyl-4-acetoxythiazole
CAS No.:65752-44-5
Molecular Formula:C₁₇H₁₃NO₂S
Molecular Weight:295.362
Hs Code.:

Synonyms:2,5-diphenyl-4-acetoxythiazole

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Chemical Property of 2,5-diphenyl-4-acetoxythiazole

Chemical Property:

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Technology Process of 2,5-diphenyl-4-acetoxythiazole

There total 5 articles about 2,5-diphenyl-4-acetoxythiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 59484-42-3
4-hydroxy-2,5-diphenyl-1,3-thiazole

: 108-24-7
acetic anhydride

: 65752-44-5
2,5-diphenyl-4-acetoxythiazole

Guidance literature:: With pyridine; In dichloromethane; at 23 ℃; for 10h;
DOI:10.1021/jm00111a035

Reference yield:

: 37167-62-7,3042-81-7,61139-20-6
bromo-phenyl-acetic acid methyl ester

: 65752-44-5
2,5-diphenyl-4-acetoxythiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / pyridine / toluene / 2 h / 80 °C

2: 92 percent / pyridine / CH₂Cl₂ / 10 h / 23 °C

With pyridine; In dichloromethane; toluene;
DOI:10.1021/jm00111a035

Reference yield:

: 3704-40-3
2,5-diphenyl-1,3-thiazole

: 65752-44-5
2,5-diphenyl-4-acetoxythiazole

Guidance literature:: Multi-step reaction with 2 steps

1: maleic anhydride, aq. H₂O₂ / CHCl₃

With maleic anhydride; dihydrogen peroxide; In chloroform;
DOI:10.1248/cpb.25.3270