70985-09-0Relevant academic research and scientific papers
A concise approach to polysubstituted oxazoles from N-acyl-2-bromo enamides via a copper(i)/amino acid-catalyzed intramolecular C-O bond formation
Liu, Bingjie,Zhang, Yueteng,Huang, Gang,Zhang, Xinting,Niu, Pengfei,Wu, Jie,Yu, Wenquan,Chang, Junbiao
, p. 3912 - 3923 (2014/06/09)
A straightforward and efficient copper(i)/amino acid-catalyzed intramolecular Ullmann-type C-O coupling reaction has been developed. This protocol affords a facile methodology for the synthesis of a series of novel 2,4,5-substituted oxazoles from readily accessible N-acyl-2-bromo enamides under mild conditions. This journal is the Partner Organisations 2014.
A practical and efficient synthesis of 2,5-disubstituted-3,5-dihydro- imidazol-4-ones from oxazolones
Chavez, Flavio,Pavy, Caslin,Williamson, Thomas,Cleary, Thomas
experimental part, p. 3321 - 3327 (2012/09/21)
An alternative procedure for the synthesis of 2,5-disubstituted-3,5- dihydro-imidazol-4-ones from substituted oxazolones was evaluated. The initial oxazolone ring-opening reaction was examined with a variety of ammonia source compounds followed by the sub
Derivatives of α,β-dehydro amino acids: III. Reaction of 4-arylmethylidene-4,5-dihydro-1,3-oxazol-5-ones with hexamethyldisilazane
Topuzyan,Arutyunyan,Oganesyan
, p. 868 - 871 (2008/03/11)
4-Arylmethylidene-4,5-dihydro-1,3-oxazol-5-ones reacted with hexamethyldisilazane in ethyl acetate, acetonitrile, or DMF at room temperature to give mainly 2-acylamino-3-arylmethylideneprop-2-enamides, whereas in boiling DMF the corresponding 4-arylmethyl
A new synthetic route to 4-arylidene-2-phenyl-2-imidazolin-5-ones
Shafi,Sobha
, p. 378 - 379 (2007/10/03)
Condensation of aromatic aldehydes with benzoylglycine amide in saturated potassium carbonate solution yields imidazolinones 2. Eight imidazolinones have been synthesized by this method in 4460% yields. The reaction follows pathway (i) which has been prov
A new methodology for the synthesis of N-acylaminocinnamates
Rao, Ch. Chennakesava,Lalitha, Nagubandi
, p. 3 (2007/10/02)
A new synthesis of biologically active N-protected amino acids (2) and amides (4) from 4-ylidene-5(4H)-oxazolones (1) is described.
Asymmetric Hydrogenation with Chiral Aminophosphine-Rhodium Complexes and Chiral Recognition by Bisphosphine-Rhodium Complexes in the Asymmetric Hydrogenation of Olefins through the Chiral Helical Conformation of Phenyl Groups on the Phosphorus Atom
Onuma, Ken-ichi,Ito, Tomiyasu,Nakamura, Asao
, p. 2016 - 2019 (2007/10/02)
The asymmetric hydrogenation of α-acylaminocinnamic acids with the rhodium complex of (1R,2R)-1,2-bis(N-diphenylphosphino-N-methylamino)cyclohexane has been reported to give preferentially (S)-amino acids.On the contrary, it has been found that the enanti
