2-(3,4-dihydro-[1]naphthyl)-anisole

Base Information

• Chemical Name: 2-(3,4-dihydro-[1]naphthyl)-anisole
• CAS No.: 116400-74-9
• Molecular Formula: C₁₇H₁₆O
• Molecular Weight: 236.313
• Mol file: 116400-74-9.mol

Synonyms:2-(3,4-dihydro-[1]naphthyl)-anisole

Chemical Property of 2-(3,4-dihydro-[1]naphthyl)-anisole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3,4-dihydro-[1]naphthyl)-anisole

There total 5 articles about 2-(3,4-dihydro-[1]naphthyl)-anisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxyphenyl magnesium bromide (13139-86-1) → 2-(3,4-dihydro-[1]naphthyl)-anisole (116400-74-9)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether; benzene / 20 °C

With diethyl ether; benzene;

DOI:10.1021/ja01182a018

Reference yield:

(+/-)-1-Hydroxy-1-(2-methoxy-phenyl)-1.2.3.4-tetrahydro-naphthalin (408313-37-1) → 2-(3,4-dihydro-[1]naphthyl)-anisole (116400-74-9)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 6h; Reflux;

DOI:10.1002/anie.201408929

Reference yield:

2-methoxyphenylmagnesium bromide (16750-63-3) → 2-(3,4-dihydro-[1]naphthyl)-anisole (116400-74-9)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether / 0 °C

2: toluene-4-sulfonic acid / toluene / 6 h / Reflux

With toluene-4-sulfonic acid; In diethyl ether; toluene;

DOI:10.1002/anie.201408929

upstream raw materials:

formic acid

(+/-)-1-Hydroxy-1-(2-methoxy-phenyl)-1.2.3.4-tetrahydro-naphthalin

4-methoxyphenyl magnesium bromide

3,4-dihydronaphthalene-1(2H)-one

Downstream raw materials:

1-(2-methoxyphenyl)naphthalene

1-(2′-hydroxyphenyl)naphthalene

benzo[b]naphtho[1,8-de]pyran