2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethanol

Base Information

• Chemical Name: 2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethanol
• CAS No.: 859511-46-9
• Molecular Formula: C₂₀H₂₄O₆
• Molecular Weight: 360.407
• Mol file: 859511-46-9.mol

Synonyms:2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethanol

Chemical Property of 2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethanol

There total 2 articles about 2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.2%

combrestatin A4 (117048-62-1,117048-59-6) + 2-bromoethanol (540-51-2) → 2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethanol (859511-46-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃;

DOI:10.1016/j.ejmech.2018.07.016

Reference yield: 90.0%

[1,3]-dioxolan-2-one (96-49-1) + combrestatin A4 (117048-62-1,117048-59-6) → 2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethanol (859511-46-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 24h;

DOI:10.1021/jm0205797

Reference yield: 95.0%

2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethanol (859511-46-9) + methanesulfonyl chloride (124-63-0) → Methanesulfonic acid 2-{2-methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethyl ester

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 ℃; for 0.5h;

DOI:10.1021/jm0205797

upstream raw materials:

[1,3]-dioxolan-2-one

combrestatin A₄

2-bromoethanol