2,3-difluoro-4-methoxypropiophenone

Base Information

• Chemical Name: 2,3-difluoro-4-methoxypropiophenone
• CAS No.: 1093857-88-5
• Molecular Formula: C₁₀H₁₀F₂O₂
• Molecular Weight: 200.185
• Mol file: 1093857-88-5.mol

Synonyms:2,3-Difluoro-4-methoxy-1-propionylbenzene

Chemical Property of 2,3-difluoro-4-methoxypropiophenone

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-difluoro-4-methoxypropiophenone

There total 1 articles about 2,3-difluoro-4-methoxypropiophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propionyl chloride (79-03-8) + 2.3-difluoroanisole (134364-69-5) → 2,3-Difluoro-4-methoxy-1-propionylbenzene (1093857-88-5)

Guidance literature:

With aluminum (III) chloride; In nitromethane; at 20 ℃; for 18h;

Reference yield:

bromoacetic acid tert-butyl ester (5292-43-3) + 2,3-Difluoro-4-methoxy-1-propionylbenzene (1093857-88-5) → C16H20F2O4

Guidance literature:

2,3-Difluoro-4-methoxy-1-propionylbenzene; With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

bromoacetic acid tert-butyl ester; In tetrahydrofuran; at 20 ℃; for 1.5h;

upstream raw materials:

propionyl chloride

2.3-difluoroanisole

Refernces