methylenebisphosphonic acid tribenzyl methyl ester

Base Information

Chemical Name:methylenebisphosphonic acid tribenzyl methyl ester
CAS No.:166049-85-0
Molecular Formula:C₂₃H₂₆O₆P₂
Molecular Weight:460.403
Hs Code.:

Synonyms:methylenebisphosphonic acid tribenzyl methyl ester

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Chemical Property of methylenebisphosphonic acid tribenzyl methyl ester

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Technology Process of methylenebisphosphonic acid tribenzyl methyl ester

There total 2 articles about methylenebisphosphonic acid tribenzyl methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 710-09-8
methyl-phosphonic acid benzyl methyl ester

: 538-37-4
dibenzyl phosphochloridate

: 166049-85-0
methylenebisphosphonic acid tribenzyl methyl ester

Guidance literature:: methyl-phosphonic acid benzyl methyl ester; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

dibenzyl phosphochloridate; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Further stages.;
DOI:10.1002/1521-3765(20021018)8:20<4649::AID-CHEM4649>3.0.CO;2-M