(S)-2-tert-butyloxycarbonylamino-3-[2’-methoxy-5’-(4’’,4’’,5’’,5’’-tetramethyl 1’’,3’’,2’’-dioxaborolane-2’’-yl)phenyl]-propionic acid methylester

Base Information

Chemical Name:(S)-2-tert-butyloxycarbonylamino-3-[2’-methoxy-5’-(4’’,4’’,5’’,5’’-tetramethyl 1’’,3’’,2’’-dioxaborolane-2’’-yl)phenyl]-propionic acid methylester
CAS No.:1095089-35-2
Molecular Formula:C₂₂H₃₄BNO₇
Molecular Weight:435.325
Hs Code.:

Synonyms:(S)-2-tert-butyloxycarbonylamino-3-[2’-methoxy-5’-(4’’,4’’,5’’,5’’-tetramethyl 1’’,3’’,2’’-dioxaborolane-2’’-yl)phenyl]-propionic acid methylester

Suppliers and Price of (S)-2-tert-butyloxycarbonylamino-3-[2’-methoxy-5’-(4’’,4’’,5’’,5’’-tetramethyl 1’’,3’’,2’’-dioxaborolane-2’’-yl)phenyl]-propionic acid methylester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-tert-butyloxycarbonylamino-3-[2’-methoxy-5’-(4’’,4’’,5’’,5’’-tetramethyl 1’’,3’’,2’’-dioxaborolane-2’’-yl)phenyl]-propionic acid methylester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-tert-butyloxycarbonylamino-3-[2’-methoxy-5’-(4’’,4’’,5’’,5’’-tetramethyl 1’’,3’’,2’’-dioxaborolane-2’’-yl)phenyl]-propionic acid methylester

There total 4 articles about (S)-2-tert-butyloxycarbonylamino-3-[2’-methoxy-5’-(4’’,4’’,5’’,5’’-tetramethyl 1’’,3’’,2’’-dioxaborolane-2’’-yl)phenyl]-propionic acid methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1095089-26-1
(S)-2-(tert-butyloxycarbonyl)amino-3-(2-methoxy-5-iodphenyl)propionic acid methyl ester

: 73183-34-3
bis(pinacol)diborane

: 1095089-35-2
(S)-2-tert-butyloxycarbonylamino-3-[2’-methoxy-5’-(4’’,4’’,5’’,5’’-tetramethyl 1’’,3’’,2’’-dioxaborolane-2’’-yl)phenyl]-propionic acid methylester

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In dimethyl sulfoxide; at 80 ℃; for 16h; Inert atmosphere;
DOI:10.1039/b811583d

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1095089-35-2
(S)-2-tert-butyloxycarbonylamino-3-[2’-methoxy-5’-(4’’,4’’,5’’,5’’-tetramethyl 1’’,3’’,2’’-dioxaborolane-2’’-yl)phenyl]-propionic acid methylester

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / 1,4-dioxane; water / 16.17 h / 0 - 20 °C / Inert atmosphere

2: potassium carbonate / acetone / 20 h / Inert atmosphere; Reflux

3: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / dimethyl sulfoxide / 4 h / 80 °C / Inert atmosphere

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; potassium carbonate; sodium hydroxide; In 1,4-dioxane; water; dimethyl sulfoxide; acetone;
DOI:10.1002/asia.201000908

Reference yield:

: 1095089-33-0
(S)-2-amino-3-(5'-iodo-2'-methoxyphenyl)propanoic acid hydrochloride

: 1095089-35-2
(S)-2-tert-butyloxycarbonylamino-3-[2’-methoxy-5’-(4’’,4’’,5’’,5’’-tetramethyl 1’’,3’’,2’’-dioxaborolane-2’’-yl)phenyl]-propionic acid methylester

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / 1,4-dioxane; water / 16.17 h / 0 - 20 °C / Inert atmosphere

2: potassium carbonate / acetone / 20 h / Inert atmosphere; Reflux

3: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / dimethyl sulfoxide / 4 h / 80 °C / Inert atmosphere

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; potassium carbonate; sodium hydroxide; In 1,4-dioxane; water; dimethyl sulfoxide; acetone;
DOI:10.1002/asia.201000908