2-[2-bromo-8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-propan-2-ol

Base Information

Chemical Name:2-[2-bromo-8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-propan-2-ol
CAS No.:1319068-87-5
Molecular Formula:C₁₅H₁₃BrClN₃O
Molecular Weight:366.645
Hs Code.:

Synonyms:2-[2-bromo-8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-propan-2-ol

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Chemical Property of 2-[2-bromo-8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-propan-2-ol

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Technology Process of 2-[2-bromo-8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-propan-2-ol

There total 6 articles about 2-[2-bromo-8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 1319068-85-3
2-[2-Amino-8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-propan-2-ol

: 1319069-84-5
1-[2-amino-8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-ethanone

: 1319068-87-5
2-[2-bromo-8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-propan-2-ol

: C₁₄H₉BrClN₃O

Guidance literature:: With tert.-butylnitrite; copper(ll) bromide; In acetonitrile; at 60 - 75 ℃; for 3h; Inert atmosphere;

Reference yield: 48.0%

: 1319068-85-3
2-[2-Amino-8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-propan-2-ol

: 1319068-87-5
2-[2-bromo-8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-propan-2-ol

Guidance literature:: With tert.-butylnitrite; copper(ll) bromide; In acetonitrile; at 60 - 75 ℃; for 3h; Inert atmosphere;

Reference yield:

: 1319068-84-2
2-(2-amino-8-bromo-[1,2,4]triazolo[1,5-a]pyridin-5-yl)-propan-2-ol

: 1329672-66-3
1-(2-amino-8-bromo-[1,2,4]triazolo[1,5-a]pyridin-5-yl)-ethanone

: 1679-18-1
4-Chlorophenylboronic acid

: 1319068-87-5
2-[2-bromo-8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-propan-2-ol

Guidance literature:: 2-(2-amino-8-bromo-[1,2,4]triazolo[1,5-a]pyridin-5-yl)-propan-2-ol; 1-(2-amino-8-bromo-[1,2,4]triazolo[1,5-a]pyridin-5-yl)-ethanone; 4-Chlorophenylboronic acid; With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; water; at 90 ℃; for 1.5h; Inert atmosphere;

With tert.-butylnitrite; copper(ll) bromide; In acetonitrile; at 60 - 75 ℃; for 3h; Inert atmosphere;