N-(tert-butoxycarbonyl)-6-methoxyanthranilic acid

Base Information

Chemical Name:N-(tert-butoxycarbonyl)-6-methoxyanthranilic acid
CAS No.:136247-94-4
Molecular Formula:C₁₃H₁₇NO₅
Molecular Weight:267.282
Hs Code.:

Synonyms:N-(tert-butoxycarbonyl)-6-methoxyanthranilic acid

Suppliers and Price of N-(tert-butoxycarbonyl)-6-methoxyanthranilic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(tert-butoxycarbonyl)-6-methoxyanthranilic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

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Technology Process of N-(tert-butoxycarbonyl)-6-methoxyanthranilic acid

There total 5 articles about N-(tert-butoxycarbonyl)-6-methoxyanthranilic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 124-38-9,18923-20-1
carbon dioxide

: 60144-52-7
tert-butyl 3-methoxyphenylcarbamate

: 136247-94-4
N-(tert-butoxycarbonyl)-6-methoxyanthranilic acid

Guidance literature:: tert-butyl 3-methoxyphenylcarbamate; With n-butyllithium; In tetrahydrofuran; hexane; at 0 - 40 ℃; for 0.025h; Flow reactor;

carbon dioxide; In tetrahydrofuran; hexane; at 40 ℃; for 0.0416667h; Flow reactor;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 53600-33-2
6-methoxyanthranilic acid

: 136247-94-4
N-(tert-butoxycarbonyl)-6-methoxyanthranilic acid

Guidance literature:: With triethylamine; In acetonitrile; for 18h;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 136247-94-4
N-(tert-butoxycarbonyl)-6-methoxyanthranilic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / tetrahydrofuran / 48 h / 50 °C

2: 1) t-BuLi / 1) THF, 2) r.t., 6 h

With tert.-butyl lithium; In tetrahydrofuran;
DOI:10.1021/jo00023a036