3-formyl-3,5-dimethoxyphenyl trifluoromethanesulphonate

Base Information

• Chemical Name: 3-formyl-3,5-dimethoxyphenyl trifluoromethanesulphonate
• CAS No.: 337375-98-1
• Molecular Formula: C₁₀H₉F₃O₆S
• Molecular Weight: 314.239
• Mol file: 337375-98-1.mol

Synonyms:3-formyl-3,5-dimethoxyphenyl trifluoromethanesulphonate

Chemical Property of 3-formyl-3,5-dimethoxyphenyl trifluoromethanesulphonate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-formyl-3,5-dimethoxyphenyl trifluoromethanesulphonate

There total 1 articles about 3-formyl-3,5-dimethoxyphenyl trifluoromethanesulphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

2-hydroxy-4,6-dimethoxybenzaldehyde (708-76-9) + trifluoromethylsulfonic anhydride (358-23-6) → 3-formyl-3,5-dimethoxyphenyl trifluoromethanesulphonate (337375-98-1)

Guidance literature:

With triethylamine; In dichloromethane; at -20 - 20 ℃; for 4h; Inert atmosphere;

DOI:10.1002/ejoc.200900195

Reference yield: 44.0%

ethanol (64-17-5) + carbon monoxide (201230-82-2) + 3-formyl-3,5-dimethoxyphenyl trifluoromethanesulphonate (337375-98-1) → 3-ethoxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (1174751-62-2) + 3,5-dimethoxy-2-formyl ethylbenzoate (308818-44-2)

Guidance literature:

With 1,3-bis-(diphenylphosphino)propane; palladium diacetate; triethylamine; In dimethyl sulfoxide; at 130 ℃; for 12h; Mechanism;

DOI:10.1002/ejoc.200900195

Reference yield:

3-formyl-3,5-dimethoxyphenyl trifluoromethanesulphonate (337375-98-1) + bis(pinacol)diborane (73183-34-3) → 2,4-dimethoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (1265360-45-9)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate;

DOI:10.1021/tx500122x

upstream raw materials:

2-hydroxy-4,6-dimethoxybenzaldehyde

trifluoromethylsulfonic anhydride

Downstream raw materials:

3-ethoxy-4,6-dimethoxy-2-benzofuran-1(3H)-one

3,5-dimethoxy-2-formyl ethylbenzoate

2,4-dimethoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde