4-acetoxy-2,6-dibromo-4-carbamoylmethylcyclohexa-2,5-dien-1-one

Base Information

• Chemical Name: 4-acetoxy-2,6-dibromo-4-carbamoylmethylcyclohexa-2,5-dien-1-one
• CAS No.: 153535-66-1
• Molecular Formula: C₁₀H₉Br₂NO₄
• Molecular Weight: 366.994
• Mol file: 153535-66-1.mol

Synonyms:4-acetoxy-2,6-dibromo-4-carbamoylmethylcyclohexa-2,5-dien-1-one

Chemical Property of 4-acetoxy-2,6-dibromo-4-carbamoylmethylcyclohexa-2,5-dien-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-acetoxy-2,6-dibromo-4-carbamoylmethylcyclohexa-2,5-dien-1-one

There total 7 articles about 4-acetoxy-2,6-dibromo-4-carbamoylmethylcyclohexa-2,5-dien-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

2-(3,5-dibromo-4-hydroxyphenyl)acetamide (17194-96-6) + lead(IV) tetraacetate (546-67-8) → 2,6-dibromo-4-hydroxy-4-carbamoylmethylcyclohexa-2,5-dien-1-one (17194-81-9) + 4-acetoxy-2,6-dibromo-4-carbamoylmethylcyclohexa-2,5-dien-1-one (153535-66-1)

Guidance literature:

In acetic acid; at 20 ℃; for 5h;

DOI:10.1023/A:1012799002863

Reference yield:

(3,5-dibromo-4-hydroxyphenyl)acetic acid (24744-58-9) → 4-acetoxy-2,6-dibromo-4-carbamoylmethylcyclohexa-2,5-dien-1-one (153535-66-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 98 percent / H₂SO₄ / benzene / Heating

2: 98 percent / NH₃; NaCN / methanol / 45 h / 45 °C

3: 36 percent / acetic acid / 5 h / 20 °C

With sulfuric acid; sodium cyanide; ammonia; In methanol; acetic acid; benzene;

DOI:10.1023/A:1012799002863

Reference yield:

3,5-dibromo-4-hydroxyphenylacetic acid ethyl ester (24744-59-0) → 4-acetoxy-2,6-dibromo-4-carbamoylmethylcyclohexa-2,5-dien-1-one (153535-66-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / NH₃; NaCN / methanol / 45 h / 45 °C

2: 36 percent / acetic acid / 5 h / 20 °C

With sodium cyanide; ammonia; In methanol; acetic acid;

DOI:10.1023/A:1012799002863

upstream raw materials:

2-(3,5-dibromo-4-hydroxyphenyl)acetamide

lead(IV) tetraacetate

4-hydroxyphenylacetate

3,5-dibromo-4-hydroxyphenylacetic acid ethyl ester