6-(O-Phosphorylcholine)hydroxyhexanoic Acid

Base Information

• Chemical Name: 6-(O-Phosphorylcholine)hydroxyhexanoic Acid
• CAS No.: 73839-24-4
• Molecular Formula: C11H24 N O6 P
• Molecular Weight: 0
• Mol file: 73839-24-4.mol

Synonyms:2-[[[(5-Carboxypentyl)oxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-ethanaminium Inner Sal;6-(O-Phosphorylcholine)hydroxyhexanoic Acid;2-[[[(5-Carboxypentyl)oxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-ethanaminium Inner Salt

Chemical Property of 6-(O-Phosphorylcholine)hydroxyhexanoic Acid

Chemical Property:

• PSA: 105.70000
• LogP: 0.13650
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility.: Methanol (Slightly), Water (Slightly)

Purity/Quality:

98%Min ^*data from raw suppliers

6-(O-Phosphorylcholine)hydroxyhexanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A novel phosphorylcholine ester for probes in immunological studies A novel phosphorylcholine ester for probes in immunological studies.

Technology Process of 6-(O-Phosphorylcholine)hydroxyhexanoic Acid

There total 9 articles about 6-(O-Phosphorylcholine)hydroxyhexanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

tert-butyl 6-(O-phosphorylcholine)hydroxyhexanoate (73839-23-3) → 6-(O-phosphorylcholine)hydroxyhexanoic acid (73839-24-4)

Guidance literature:

With Dowex-50(H+) resin; In water; for 0.5h; steam bath;

DOI:10.1021/jo01303a029

Reference yield: 80.0%

Ethyl 6-(O-phosphorylcholine)hydroxyhexanoate (134046-84-7) → 6-(O-phosphorylcholine)hydroxyhexanoic acid (73839-24-4)

Guidance literature:

With tetra(n-butyl)ammonium hydroxide; at 23 ℃; for 12h;

Reference yield: 40.0%

tert-butyl 6-(O-(2-bromoethyl)phosphoryl)hydroxyhexanoate (73839-25-5) + trimethylamine (75-50-3) → 6-(O-phosphorylcholine)hydroxyhexanoic acid (73839-24-4) + tert-butyl 6-(O-phosphorylcholine)hydroxyhexanoate (73839-23-3)

Guidance literature:

In chloroform; for 8h; Heating;

DOI:10.1021/jo01303a029

upstream raw materials:

tert-butyl 6-(O-phosphorylcholine)hydroxyhexanoate

tert-butyl 6-(O-(2-bromoethyl)phosphoryl)hydroxyhexanoate

trimethylamine

Ethyl 6-(O-phosphorylcholine)hydroxyhexanoate

Downstream raw materials:

p-nitrophenyl 6-(O-phosphorylcholine)hydroxyhexanoate