Technology Process of C18H22ClN3O
There total 1 articles about C18H22ClN3O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran;
at 50 ℃;
for 18h;
- Guidance literature:
-
With
sodium acetate;
1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 18h;
under 3750.38 Torr;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium acetate / palladium diacetate; 1,1'-bis-(diphenylphosphino)ferrocene / N,N-dimethyl-formamide / 18 h / 80 °C / 3750.38 Torr
2: water; lithium hydroxide / tetrahydrofuran / 20 °C
3: N-ethyl-N,N-diisopropylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / N,N-dimethyl-formamide / 2 h
4: trifluoroacetic acid / dichloromethane
With
water; sodium acetate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; lithium hydroxide;
1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;