(Z)-4,4,5,5-tetramethyl-2-(4-(fluoro)styryl)-1,3,2-dioxaborolane

Base Information

• Chemical Name: (Z)-4,4,5,5-tetramethyl-2-(4-(fluoro)styryl)-1,3,2-dioxaborolane
• CAS No.: 1394797-23-9
• Molecular Formula: C₁₄H₁₈BFO₂
• Molecular Weight: 248.105
• Mol file: 1394797-23-9.mol

Synonyms:(Z)-4,4,5,5-tetramethyl-2-(4-(fluoro)styryl)-1,3,2-dioxaborolane

Chemical Property of (Z)-4,4,5,5-tetramethyl-2-(4-(fluoro)styryl)-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-4,4,5,5-tetramethyl-2-(4-(fluoro)styryl)-1,3,2-dioxaborolane

There total 3 articles about (Z)-4,4,5,5-tetramethyl-2-(4-(fluoro)styryl)-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1-ethynyl-4-fluorobenzene (766-98-3) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → (Z)-4,4,5,5-tetramethyl-2-(4-(fluoro)styryl)-1,3,2-dioxaborolane (1394797-23-9)

Guidance literature:

With C₁₉H₄₁FeN₃P₂; In tetrahydrofuran; benzene-d6; at 20 ℃; for 3h; stereoselective reaction; Inert atmosphere; Glovebox;

DOI:10.1021/jacs.7b05051

Reference yield:

1-ethynyl-4-fluorobenzene (766-98-3) → (Z)-4,4,5,5-tetramethyl-2-(4-(fluoro)styryl)-1,3,2-dioxaborolane (1394797-23-9) + 2-[(1E)-2-(4-fluorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (504433-86-7)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene-d6 / 15 h / 20 °C / Inert atmosphere

2: benzene-d6 / 4 h / Inert atmosphere

In benzene-d6;

DOI:10.1039/d1dt00277e

Reference yield:

C30H30CoFN3O2 + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → (Z)-4,4,5,5-tetramethyl-2-(4-(fluoro)styryl)-1,3,2-dioxaborolane (1394797-23-9) + 2-[(1E)-2-(4-fluorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (504433-86-7)

Guidance literature:

In benzene-d6; for 4h; Inert atmosphere;

DOI:10.1039/d1dt00277e

upstream raw materials:

1-ethynyl-4-fluorobenzene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

Downstream raw materials:

2-[(1E)-2-(4-fluorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane