N-benzyloxycarbonyl-L-alanyl-2-aminoisobutyric acid methyl ester

Base Information

Chemical Name:N-benzyloxycarbonyl-L-alanyl-2-aminoisobutyric acid methyl ester
CAS No.:112142-82-2
Molecular Formula:C₁₆H₂₂N₂O₅
Molecular Weight:322.361
Hs Code.:

Synonyms:N-benzyloxycarbonyl-L-alanyl-2-aminoisobutyric acid methyl ester

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Chemical Property of N-benzyloxycarbonyl-L-alanyl-2-aminoisobutyric acid methyl ester

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Technology Process of N-benzyloxycarbonyl-L-alanyl-2-aminoisobutyric acid methyl ester

There total 8 articles about N-benzyloxycarbonyl-L-alanyl-2-aminoisobutyric acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1142-20-7
N-Cbz-Ala

: 15028-41-8
methyl 2-aminoisobutyrate hydrochloride

: 112142-82-2
N-benzyloxycarbonyl-L-alanyl-2-aminoisobutyric acid methyl ester

Guidance literature:: With P(p-CH₃OC₆H₄)3; 6-(3,5-bis(trifluoromethyl)phenyl)-1H,4H-2aλ³-ioda-2,3-dioxacyclopenta[hi]indene-1,4-dione; triethylamine; In 1,2-dichloro-ethane; at 20 ℃; for 0.166667h;
DOI:10.1021/acs.orglett.5b02045

Reference yield: 89.0%

: 67-56-1
methanol

: 112142-71-9
N-benzyloxycarbonyl-L-alanyl-N¹,N¹,2-trimethylalanin-amid

: 112142-82-2
N-benzyloxycarbonyl-L-alanyl-2-aminoisobutyric acid methyl ester

Guidance literature:: With hydrogenchloride; for 4h; Ambient temperature;
DOI:10.1002/hlca.19870700213

Reference yield: 11.0%

: 13257-67-5
2-amino-2-methylpropionic acid methyl ester

: 210840-42-9
N-(Benzyloxycarbonyl)alanine (3,5-di-tert-butyl-4-hydroxyphenyl)ester

: 112142-82-2
N-benzyloxycarbonyl-L-alanyl-2-aminoisobutyric acid methyl ester

Guidance literature:: With 2,6-dimethylpyridine; 2,6-lutidinium perchlorate; In dichloromethane; Ambient temperature; electrochemical reaction: platinum electrodes containing 10percent od iridium); divided cells with a ceramic tube as diaphragm; Et₄NBF₄ as supporting electrolyte;
DOI:10.1515/znb-1998-0717