Technology Process of 6-bromo-1-chlorocyclohex-1-ene
There total 5 articles about 6-bromo-1-chlorocyclohex-1-ene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-chlorocyclohex-2-en-1-ol;
With
carbon tetrabromide;
In
diethyl ether;
at 0 ℃;
for 0.0833333h;
With
triphenylphosphine;
In
diethyl ether;
at 0 - 25 ℃;
for 3h;
DOI:10.1021/acs.orglett.8b00967
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydrogenchloride; 3-chloro-benzenecarboperoxoic acid / water; N,N-dimethyl-formamide / 0.5 h / 25 °C
2.1: cerium(III) chloride heptahydrate; sodium tetrahydroborate / methanol / 3.5 h / 0 - 25 °C / Inert atmosphere
3.1: carbon tetrabromide / diethyl ether / 0.08 h / 0 °C
3.2: 3 h / 0 - 25 °C
With
hydrogenchloride; sodium tetrahydroborate; carbon tetrabromide; cerium(III) chloride heptahydrate; 3-chloro-benzenecarboperoxoic acid;
In
methanol; diethyl ether; water; N,N-dimethyl-formamide;
DOI:10.1021/acs.orglett.8b00967
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: cerium(III) chloride heptahydrate; sodium tetrahydroborate / methanol / 3.5 h / 0 - 25 °C / Inert atmosphere
2.1: carbon tetrabromide / diethyl ether / 0.08 h / 0 °C
2.2: 3 h / 0 - 25 °C
With
sodium tetrahydroborate; carbon tetrabromide; cerium(III) chloride heptahydrate;
In
methanol; diethyl ether;
DOI:10.1021/acs.orglett.8b00967
