C₂₀H₁₇NO₅

Base Information

Chemical Name:C₂₀H₁₇NO₅
CAS No.:951305-30-9
Molecular Formula:C₂₀H₁₇NO₅
Molecular Weight:351.359
Hs Code.:

C<sub>20</sub>H<sub>17</sub>NO<sub>5</sub>

Synonyms:C₂₀H₁₇NO₅

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₀H₁₇NO₅

Chemical Property:

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Technology Process of C₂₀H₁₇NO₅

There total 2 articles about C₂₀H₁₇NO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 863203-65-0
2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester

: C₂₀H₁₇NO₅

: 951305-30-9
C₂₀H₁₇NO₅

: 22204-53-1
(2S)-2-(6-methoxy(2-naphthyl))propanoic acid

: 23979-41-1
(R)-2-(6-methoxy-2-naphthyl)propionic acid

Guidance literature:: 2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester; With Pseudomonas aeruginosa lipase Met₁₆Ala/Leu₁₇Phe/Leu₁₆₂Asn mutant; In acetonitrile; at 30 ℃; for 1.5h; pH=7.5; aq. phosphate buffer; Resolution of racemate; Enzymatic reaction;

With hydrogenchloride; In water; acetonitrile; enantioselective reaction;
DOI:10.1021/ja1030479

Reference yield:

: 863203-65-0
2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester

: C₂₀H₁₇NO₅

: 951305-30-9
C₂₀H₁₇NO₅

: 23981-80-8
naproxen

Guidance literature:: With Candida antarctica lipase B RG₄₀₁ mutant; water; In aq. phosphate buffer; acetonitrile; at 30 ℃; for 20h; pH=7.5; Reagent/catalyst; Time; enantioselective reaction; Resolution of racemate; Enzymatic reaction;
DOI:10.1021/ja310455t

Reference yield:

: 951305-30-9
C₂₀H₁₇NO₅

: 23979-41-1
(R)-2-(6-methoxy-2-naphthyl)propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate; (R)-5-benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate / chloroform / 24 - 26 °C / Molecular sieve

2: palladium 10% on activated carbon; hydrogen / ethanol; tetrahydrofuran / 24 h / 24 - 26 °C

With palladium 10% on activated carbon; (R)-5-benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; hydrogen; caesium carbonate; In tetrahydrofuran; ethanol; chloroform;
DOI:10.1021/jacs.6b00406