2-bromo-N-(1-phenylethyl)aniline

Base Information

• Chemical Name: 2-bromo-N-(1-phenylethyl)aniline
• CAS No.: 1019544-78-5
• Molecular Formula: C₁₄H₁₄BrN
• Molecular Weight: 276.176
• Mol file: 1019544-78-5.mol

Synonyms:2-bromo-N-(1-phenylethyl)aniline

Chemical Property of 2-bromo-N-(1-phenylethyl)aniline

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-bromo-N-(1-phenylethyl)aniline

There total 5 articles about 2-bromo-N-(1-phenylethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C14H12BrN (673459-42-2) → 2-bromo-N-(1-phenylethyl)aniline (1019544-78-5)

Guidance literature:

With triethylsilane; [(η5-pentamethylcyclopentadienyl)Ir(2-phenylpyridine(1-))Cl]; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate; In dichloromethane; at 25 ℃; for 7h; Inert atmosphere;

DOI:10.1039/c4cy01233j

Reference yield: 92.0%

phenylacetylene (536-74-3) + 2-bromoaniline (615-36-1) → 2-bromo-N-(1-phenylethyl)aniline (1019544-78-5)

Guidance literature:

phenylacetylene; 2-bromoaniline; With silver trifluoromethanesulfonate; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; at 20 ℃; for 36h; Sealed tube;

With borane-THF; at -20 ℃; for 2h; Sealed tube;

DOI:10.1002/adsc.201300785

Reference yield: 70.0%

1-phenylethyl 2,2,2-trichloroacetimidate (99421-72-4) + 2-bromoaniline (615-36-1) → 2-bromo-N-(1-phenylethyl)aniline (1019544-78-5)

Guidance literature:

With camphor-10-sulfonic acid; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/jo5027222

upstream raw materials:

(1-bromoethyl)benzne

2-bromoaniline

phenylacetylene

1-phenylethyl 2,2,2-trichloroacetimidate

Downstream raw materials:

3-bromo-N-(1-phenylethyl)-[1,1'-biphenyl]-4-amine

2-(6-(3,5-di-tert-butyl-2-(methoxymethoxy)phenyl)pyridin-2-yl)-N-(1-phenylethyl)aniline

2,4-di-tert-butyl-6-(6-(2-((1-phenylethyl)amino)phenyl)pyridin-2-yl)phenol