5-(benzyloxy)-2-<(benzyloxy)carbamido>-2-indancarboxylic acid

Base Information

Chemical Name:5-(benzyloxy)-2-<(benzyloxy)carbamido>-2-indancarboxylic acid
CAS No.:84802-82-4
Molecular Formula:C₂₅H₂₃NO₅
Molecular Weight:417.461
Hs Code.:

Synonyms:5-(benzyloxy)-2-<(benzyloxy)carbamido>-2-indancarboxylic acid

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Chemical Property of 5-(benzyloxy)-2-<(benzyloxy)carbamido>-2-indancarboxylic acid

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Technology Process of 5-(benzyloxy)-2-<(benzyloxy)carbamido>-2-indancarboxylic acid

There total 2 articles about 5-(benzyloxy)-2-<(benzyloxy)carbamido>-2-indancarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 33709-81-8
2-amino-5-hydroxy-2-indancarboxylic acid

: 84802-82-4
5-(benzyloxy)-2-<(benzyloxy)carbamido>-2-indancarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 2N aq. NaOH, CuSO₄, 3.) aq. HCl

2: 1.) 2 N aq. NaOH / 1.) heating, 2.) RT, 60 h

With hydrogenchloride; sodium hydroxide; copper(II) sulfate;
DOI:10.1021/jm00359a024

Reference yield:

: 100-39-0
benzyl bromide

: 84802-82-4
5-(benzyloxy)-2-<(benzyloxy)carbamido>-2-indancarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 2N aq. NaOH, CuSO₄, 3.) aq. HCl

2: 1.) 2 N aq. NaOH / 1.) heating, 2.) RT, 60 h

With hydrogenchloride; sodium hydroxide; copper(II) sulfate;
DOI:10.1021/jm00359a024

Reference yield: 74.0%

: 68709-94-4
glycyl-glycyl-(S)phenylalanyl-(S)leucine methyl ester

: 84802-82-4
5-(benzyloxy)-2-<(benzyloxy)carbamido>-2-indancarboxylic acid

: 84802-83-5
<<5-(benzyloxy)-2-<(benzyloxy)carbamido>-2-indanyl>carbonyl>glycylglycyl-L-phenylalanyl-L-leucine methyl ester

Guidance literature:: With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In dichloromethane; for 56h; Ambient temperature;
DOI:10.1021/jm00359a024