2,4-Dibromo-N-methylaniline

Base Information

• Chemical Name: 2,4-Dibromo-N-methylaniline
• CAS No.: 73557-58-1
• Molecular Formula: C7H7 Br2 N
• Molecular Weight: 264.947
• Hs Code.: 2921420090
• European Community (EC) Number: 623-446-3
• DSSTox Substance ID: DTXSID30456298
• Nikkaji Number: J2.124.798G
• Wikidata: Q82278671
• Mol file: 73557-58-1.mol

Synonyms:2,4-Dibromo-N-methylaniline;73557-58-1;2,4-dibrom-N-methylanilin;N-Methyl-2,4-dibromoaniline;SCHEMBL12301896;DTXSID30456298;MFCD08276870;AKOS009052149;2,4-DIBROMO-N-METHYLANILINE, 97%;EN300-7088312

Chemical Property of 2,4-Dibromo-N-methylaniline

Chemical Property:

• Vapor Pressure: 0.002mmHg at 25°C
• Melting Point: 44-48 °C
• Refractive Index: 1.646
• Boiling Point: 287.849°C at 760 mmHg
• Flash Point: 110 °C
• PSA: 12.03000
• Density: 1.876g/cm³
• LogP: 3.32630
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 264.89247
• Heavy Atom Count: 10
• Complexity: 108

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,4-Dibromo-N-methylaniline 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNC1=C(C=C(C=C1)Br)Br

Technology Process of 2,4-Dibromo-N-methylaniline

There total 17 articles about 2,4-Dibromo-N-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

N-methylaniline (100-61-8) → 4-bromo-N-methylaniline (6911-87-1,211060-12-7) + 2,4-dibromo-N-methylaniline (73557-58-1)

Guidance literature:

With tetra-N-butylammonium tribromide; In chloroform; for 0.0333333h;

Reference yield: 85.0%

N-methylaniline (100-61-8) → 2,4-dibromo-N-methylaniline (73557-58-1)

Guidance literature:

With 1-benzyl-1-aza-4-azoniabicyclo<2.2.2>octane bromide; calcium carbonate; In methanol; at 20 ℃; for 0.25h;

DOI:10.1081/SCC-200043274

Reference yield: 51.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2,4-dibromo-aniline (615-57-6) → 6,8-dibromo-3-(2,4-dibromophenyl)-1,2,3,4-tetrahydroquinazoline (1042268-53-0) + (+/-)-2,4,8,10-tetrabromo-6H,12H-5,11-methanodibenzo[b,f][1,5]diazocine (1042269-21-5,1042269-33-9,929101-61-1) + 2,4-dibromo-N-methylaniline (73557-58-1)

Guidance literature:

With trifluoroacetic acid; at 20 ℃; for 24h;

DOI:10.1016/j.tet.2008.04.111

upstream raw materials:

N-methyl-N-nitrosoaniline

N-methylaniline

methanol

N-methyl-N-(2,4-dibromophenyl)sulfuric diamide

Downstream raw materials:

2-dimethylamino-N-(1,1-dimethylethyl)-5-formylbenzamide

5-bromo-2-dimethylamino-N-(1,1-dimethylethyl)benzamide

2-(N,N-dimethylamino)-5-bromobenzaldehyde

2,4-dibromo-N,N-dimethylaniline