(2S)-5-cyclopropyl-N-((3S)-1-(cyclopropylamino)-2-hydroxy-1-oxopentan-3-yl)-2-(2,2-difluoro-2-(4-fluorophenoxy)ethylamino)-4,4-difluoropentanamide

Base Information

Chemical Name:(2S)-5-cyclopropyl-N-((3S)-1-(cyclopropylamino)-2-hydroxy-1-oxopentan-3-yl)-2-(2,2-difluoro-2-(4-fluorophenoxy)ethylamino)-4,4-difluoropentanamide
CAS No.:1227087-72-0
Molecular Formula:C₂₄H₃₂F₅N₃O₄
Molecular Weight:521.528
Hs Code.:

Synonyms:(2S)-5-cyclopropyl-N-((3S)-1-(cyclopropylamino)-2-hydroxy-1-oxopentan-3-yl)-2-(2,2-difluoro-2-(4-fluorophenoxy)ethylamino)-4,4-difluoropentanamide

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Chemical Property of (2S)-5-cyclopropyl-N-((3S)-1-(cyclopropylamino)-2-hydroxy-1-oxopentan-3-yl)-2-(2,2-difluoro-2-(4-fluorophenoxy)ethylamino)-4,4-difluoropentanamide

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Technology Process of (2S)-5-cyclopropyl-N-((3S)-1-(cyclopropylamino)-2-hydroxy-1-oxopentan-3-yl)-2-(2,2-difluoro-2-(4-fluorophenoxy)ethylamino)-4,4-difluoropentanamide

There total 1 articles about (2S)-5-cyclopropyl-N-((3S)-1-(cyclopropylamino)-2-hydroxy-1-oxopentan-3-yl)-2-(2,2-difluoro-2-(4-fluorophenoxy)ethylamino)-4,4-difluoropentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 910544-90-0
(3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide hydrochloride

: 1227087-52-6
(S)-5-cyclopropyl-2-(2,2-difluoro-2-(4-fluorophenoxy)ethylamino)-4,4-difluoropentanoic acid

: 1227087-72-0
(2S)-5-cyclopropyl-N-((3S)-1-(cyclopropylamino)-2-hydroxy-1-oxopentan-3-yl)-2-(2,2-difluoro-2-(4-fluorophenoxy)ethylamino)-4,4-difluoropentanamide

Guidance literature:: (3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide hydrochloride; (S)-5-cyclopropyl-2-(2,2-difluoro-2-(4-fluorophenoxy)ethylamino)-4,4-difluoropentanoic acid; With 4-methyl-morpholine; HATU; In dichloromethane; at 20 ℃;

With 1-hydroxy-1,1,2-ethanetricarboxylic acid; In dichloromethane; water; ethyl acetate;