13-(2,3-dichlorophenyl)-3,3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H,13H)-trione

Base Information

• Chemical Name: 13-(2,3-dichlorophenyl)-3,3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H,13H)-trione
• CAS No.: 1278520-01-6
• Molecular Formula: C₂₃H₁₈Cl₂N₂O₃
• Molecular Weight: 441.314
• Mol file: 1278520-01-6.mol

Synonyms:13-(2,3-dichlorophenyl)-3,3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H,13H)-trione

Chemical Property of 13-(2,3-dichlorophenyl)-3,3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H,13H)-trione

Chemical Property:

Purity/Quality:

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MSDS Files:

Useful:

Technology Process of 13-(2,3-dichlorophenyl)-3,3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H,13H)-trione

There total 3 articles about 13-(2,3-dichlorophenyl)-3,3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H,13H)-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2,3-dihydrophthalazine-1,4-dione (1445-69-8) + dimedone (126-81-8) + 2,3-dichlorobenzylaldehyde (6334-18-5) → 13-(2,3-dichlorophenyl)-3,3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H,13H)-trione (1278520-01-6)

Guidance literature:

With 1-methyl-3-(4-sulfobutyl)-1H-imidazol-3-ium hydrogensulfate; at 120 ℃; for 0.666667h;

DOI:10.5560/ZNB.2012-0090

Reference yield: 89.0%

phthalic anhydride (85-44-9) + hydrazine hydrate (79785-97-0) + dimedone (126-81-8) + 2,3-dichlorobenzylaldehyde (6334-18-5) → 13-(2,3-dichlorophenyl)-3,3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H,13H)-trione (1278520-01-6)

Guidance literature:

With 1,4-dimethyl-1-(4-sulphobutyl)piperazinium hydrogen sulphate; at 80 ℃; for 0.133333h; Green chemistry;

DOI:10.1007/s11164-014-1736-0

Reference yield:

phthaloyldihydrazine (3645-45-2) + dimedone (126-81-8) + 2,3-dichlorobenzylaldehyde (6334-18-5) → 13-(2,3-dichlorophenyl)-3,3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H,13H)-trione (1278520-01-6)

Guidance literature:

In neat (no solvent); at 110 ℃; for 0.0666667h;

DOI:10.1002/aoc.4308

upstream raw materials:

2,3-dihydrophthalazine-1,4-dione

dimedone

2,3-dichlorobenzylaldehyde

phthalic anhydride