Methyl 4-(3-hydroxypyridin-2-yl)benzoate

Base Information

Chemical Name:Methyl 4-(3-hydroxypyridin-2-yl)benzoate
CAS No.:1261981-75-2
Molecular Formula:C₁₃H₁₁NO₃
Molecular Weight:229.235
Hs Code.:
DSSTox Substance ID:DTXSID80682924
Nikkaji Number:J3.535.894C
Wikidata:Q82607521

Synonyms:1261981-75-2;3-HYDROXY-2-(4-METHOXYCARBONYLPHENYL)PYRIDINE;methyl 4-(3-hydroxypyridin-2-yl)benzoate;SCHEMBL15266332;DTXSID80682924;MFCD18312262;J3.535.894C;4-(3-Hydroxy-2-pyridyl)benzoic acid methyl ester

Suppliers and Price of Methyl 4-(3-hydroxypyridin-2-yl)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl 4-(3-hydroxypyridin-2-yl)benzoate

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:229.07389321
Heavy Atom Count:17
Complexity:261

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC=C(C=C1)C2=C(C=CC=N2)O

Technology Process of Methyl 4-(3-hydroxypyridin-2-yl)benzoate

There total 6 articles about Methyl 4-(3-hydroxypyridin-2-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 67-56-1
methanol

: 1261937-73-8
4-(3-hydroxypyridin-2-yl)benzoic acid

: 1261981-75-2
methyl 4-(3-hydroxypyridin-2-yl)benzoate

Guidance literature:: With thionyl chloride; at 4 - 70 ℃; for 14h;

Reference yield: 82.0%

: C₁₅H₁₅NO₄

: 1261981-75-2
methyl 4-(3-hydroxypyridin-2-yl)benzoate

Guidance literature:: C₁₅H₁₅NO₄; With hydrogenchloride; In tetrahydrofuran; ethanol; water; at 60 ℃; for 2h;

With sodium hydrogencarbonate; In tetrahydrofuran; ethanol; water;
DOI:10.1021/acs.orglett.5b00276

Reference yield: 55.0%

: 109-00-2
3-HYDROXYPYRIDINE

: 619-45-4
4-methoxycarbonyl aniline

: 1261981-75-2
methyl 4-(3-hydroxypyridin-2-yl)benzoate

Guidance literature:: 4-methoxycarbonyl aniline; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 0.5h;

3-HYDROXYPYRIDINE; With hydrogenchloride; titanium(III) chloride; In water; for 0.416667h; regioselective reaction; Inert atmosphere;
DOI:10.1021/acs.joc.6b00894