5-(Trimethylsilyl)thiophene-2-carbonitrile

Base Information

Chemical Name:5-(Trimethylsilyl)thiophene-2-carbonitrile
CAS No.:77998-64-2
Molecular Formula:C₈H₁₁NSSi
Molecular Weight:181.334
Hs Code.:2934999090
DSSTox Substance ID:DTXSID50592364
Wikidata:Q82486441
Mol file:77998-64-2.mol

Synonyms:77998-64-2;5-Trimethylsilanyl-thiophene-2-carbonitrile;5-(trimethylsilyl)thiophene-2-carbonitrile;5-Trimethylsilylthiophene-2-carbonitrile;2-Thiophenecarbonitrile,5-(trimethylsilyl)-;C8H11NSSi;5-CYANO-2-TRIMETHYLSILYL-THIOPHENE;DTXSID50592364;MFCD09039087;AKOS006282134;SB38734;5-(Trimethylsilyl)-2-thiophenecarbonitrile;DB-253293;CS-0340116

Suppliers and Price of 5-(Trimethylsilyl)thiophene-2-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Trimethylsilanyl-thiophene-2-carbonitrile
50mg
$ 130.00

J&W Pharmlab
5-Trimethylsilanyl-thiophene-2-carbonitrile 96%
250mg
$ 325.00

J&W Pharmlab
5-Trimethylsilanyl-thiophene-2-carbonitrile 96%
100mg
$ 212.00

American Custom Chemicals Corporation
5-CYANO-2-TRIMETHYLSILYL-THIOPHENE 95.00%
1G
$ 630.00

Total 8 raw suppliers

Chemical Property of 5-(Trimethylsilyl)thiophene-2-carbonitrile

Chemical Property:

PSA：52.03000
LogP:2.16498
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:181.03814706
Heavy Atom Count:11
Complexity:188

Purity/Quality:

97% ^*data from raw suppliers

5-Trimethylsilanyl-thiophene-2-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(C)C1=CC=C(S1)C#N

Technology Process of 5-(Trimethylsilyl)thiophene-2-carbonitrile

There total 2 articles about 5-(Trimethylsilyl)thiophene-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1003-31-2
thiophene-2-carbonitrile

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 77998-64-2
2-cyano-5-trimethylsilylthiophene

Guidance literature:: With rubidium fluoride; In tetrahydrofuran; at -20 ℃; for 2h; Solvent; Temperature; regioselective reaction; Inert atmosphere;
DOI:10.1021/ol503671b

Reference yield:

: 1003-31-2
thiophene-2-carbonitrile

: 75-77-4
chloro-trimethyl-silane

: 77998-64-2
2-cyano-5-trimethylsilylthiophene

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide; Multistep reaction; 1.) Et₂O, -78 deg C, 0.5 h, 2.) Et₂O, RT, 18 h;
DOI:10.1016/S0022-328X(00)84581-7