6-(Dimethylamino)-4-methylnicotinaldehyde

Base Information

Chemical Name:6-(Dimethylamino)-4-methylnicotinaldehyde
CAS No.:764651-69-6
Molecular Formula:C₉H₁₂N₂O
Molecular Weight:164.207
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80473450
Mol file:764651-69-6.mol

Synonyms:6-(DIMETHYLAMINO)-4-METHYLNICOTINALDEHYDE;764651-69-6;6-(DIMETHYLAMINO)-4-METHYLPYRIDINE-3-CARBALDEHYDE;6-dimethylamino-4-methyl-pyridine-3-carbaldehyde;SCHEMBL1237308;DTXSID80473450;AMY17375;AKOS006286013;AB44363;CS-0331117;FT-0754550;E90118;EN300-1264457;J-518067;Z1198176756

Suppliers and Price of 6-(Dimethylamino)-4-methylnicotinaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-(Dimethylamino)-4-methylnicotinaldehyde 95+%
1g
$ 455.00

Chemenu
6-(Dimethylamino)-4-methylpyridine-3-carbaldehyde 95%
1g
$ 430.00

American Custom Chemicals Corporation
6-(DIMETHYLAMINO)-4-METHYLNICOTINALDEHYDE 95.00%
5G
$ 2656.50

Total 9 raw suppliers

Chemical Property of 6-(Dimethylamino)-4-methylnicotinaldehyde

Chemical Property:

Vapor Pressure:0.000361mmHg at 25°C
Refractive Index:1.591
Boiling Point:318.4°C at 760 mmHg
Flash Point:146.4°C
PSA：33.20000
Density:1.105g/cm³
LogP:1.26850
Storage Temp.:2-8°C
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:164.094963011
Heavy Atom Count:12
Complexity:159

Purity/Quality:

97% ^*data from raw suppliers

6-(Dimethylamino)-4-methylnicotinaldehyde 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC=C1C=O)N(C)C

Technology Process of 6-(Dimethylamino)-4-methylnicotinaldehyde

There total 2 articles about 6-(Dimethylamino)-4-methylnicotinaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 764651-68-5
5-bromo-2-dimethylamino-4-methylpyridine

: 764651-69-6
2-dimethylamino-4-methyl-5-formylpyridine

Guidance literature:: 5-bromo-2-dimethylamino-4-methylpyridine; With magnesium; ethylene dibromide; In tetrahydrofuran; for 0.5h;

N,N-dimethyl-formamide; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/jm040058e

Reference yield:

: 20173-72-2
2-(N,N-dimethylamino)-4-methylpyridine

: 764651-69-6
2-dimethylamino-4-methyl-5-formylpyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: Br₂; aq. Na₂CO₃ / CH₂Cl₂ / 0.5 h / 0 °C

2.1: Mg; 1,2-dibromoethane / tetrahydrofuran / 0.5 h

2.2: 77 percent / tetrahydrofuran / 20 °C

With bromine; sodium carbonate; magnesium; ethylene dibromide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm040058e

Reference yield: 80.0%

: 38622-91-2,36635-61-7
[(p-methylphenyl)sulfonylmethyl]isonitrile

: 764651-69-6
2-dimethylamino-4-methyl-5-formylpyridine

: 764651-70-9
2-dimethylamino-4-methyl-5-(cyanomethyl)pyridine

Guidance literature:: [(p-methylphenyl)sulfonylmethyl]isonitrile; With potassium tert-butylate; In 1,2-dimethoxyethane; at -50 ℃; for 0.166667h;

2-dimethylamino-4-methyl-5-formylpyridine; In 1,2-dimethoxyethane; at -50 ℃; for 0.5h;
DOI:10.1021/jm040058e