Azido-PEG4-4-nitrophenyl carbonate

Base Information

Chemical Name:Azido-PEG4-4-nitrophenyl carbonate
CAS No.:1422540-98-4
Molecular Formula:C₁₅H₂₀N₄O₈
Molecular Weight:384.346
Hs Code.:
Mol file:1422540-98-4.mol

Synonyms:C₁₅H₂₀N₄O₈

Suppliers and Price of Azido-PEG4-4-nitrophenyl carbonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Azido-PEG4-4-nitrophenylcarbonate
50mg
$ 265.00

BroadPharm
Azido-PEG4-4-nitrophenylcarbonate 98%
1 G
$ 890.00

Total 12 raw suppliers

Chemical Property of Azido-PEG4-4-nitrophenyl carbonate

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Azido-PEG4-4-nitrophenylcarbonate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Azido-PEG4-4-nitrophenyl carbonate is a PEG linker containing an azide group and an reactive nitrophenyl carbonate(NPC group). The NPC group is reactive towards the amino group of lysine by means of stable urethane linkages. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.

Technology Process of Azido-PEG4-4-nitrophenyl carbonate

There total 3 articles about Azido-PEG4-4-nitrophenyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 86770-67-4
2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethanol

: 7693-46-1
4-Nitrophenyl chloroformate

: 1422540-98-4
C₁₅H₂₀N₄O₈

Guidance literature:: In acetonitrile; at 0 - 20 ℃;
DOI:10.1039/c2ob26968f

Reference yield:

: 112-60-7
Tetraethylene glycol

: 1422540-98-4
C₁₅H₂₀N₄O₈

Guidance literature:: Multi-step reaction with 3 steps

1: silver(l) oxide / dichloromethane / 24 h / 0 - 20 °C

2: sodium azide / N,N-dimethyl-formamide / 12 h / 65 °C

3: acetonitrile / 0 - 20 °C

With sodium azide; silver(l) oxide; In dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1039/c2ob26968f

Reference yield:

: 65883-12-7
2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethyl methanesulfonate

: 1422540-98-4
C₁₅H₂₀N₄O₈

Guidance literature:: Multi-step reaction with 2 steps

1: sodium azide / N,N-dimethyl-formamide / 12 h / 65 °C

2: acetonitrile / 0 - 20 °C

With sodium azide; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1039/c2ob26968f