rac.-1-Stearoyl-glycerin-benzylether-⁽²⁾-phosphorsaeure-⁽³⁾-monocholinester

Base Information

• Chemical Name: rac.-1-Stearoyl-glycerin-benzylether-⁽²⁾-phosphorsaeure-⁽³⁾-monocholinester
• CAS No.: 18678-96-1
• Molecular Formula: C₃₃H₆₀NO₇P
• Molecular Weight: 613.816

Synonyms:rac.-1-Stearoyl-glycerin-benzylether-⁽²⁾-phosphorsaeure-⁽³⁾-monocholinester

Chemical Property of rac.-1-Stearoyl-glycerin-benzylether-⁽²⁾-phosphorsaeure-⁽³⁾-monocholinester

Chemical Property:

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Technology Process of rac.-1-Stearoyl-glycerin-benzylether-⁽²⁾-phosphorsaeure-⁽³⁾-monocholinester

There total 3 articles about rac.-1-Stearoyl-glycerin-benzylether-⁽²⁾-phosphorsaeure-⁽³⁾-monocholinester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-O-benzylglycerol (14690-00-7) → rac.-1-Stearoyl-glycerin-benzylether-(2)-phosphorsaeure-(3)-monocholinester (18678-96-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Py / CHCl₃

2: (i) Et₃N, (ii) /BRN= 956566/

With pyridine; In chloroform;

DOI:10.1002/jlac.19677090126

Reference yield:

benzyl chloride (100-44-7) → rac.-1-Stearoyl-glycerin-benzylether-(2)-phosphorsaeure-(3)-monocholinester (18678-96-1)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) aq. KOH, (ii) (acid hydrolysis)

2: Py / CHCl₃

3: (i) Et₃N, (ii) /BRN= 956566/

With pyridine; In chloroform;

DOI:10.1002/jlac.19677090126

Reference yield:

2-bromoethylphosphoric acid dichloride (4167-02-6) + 1-stearoyl-2-O-benzyl-rac-glycerol (18679-03-3) + trimethylamine (75-50-3) → rac.-1-Stearoyl-glycerin-benzylether-(2)-phosphorsaeure-(3)-monocholinester (18678-96-1)

Guidance literature:

Multistep reaction; (i) Et₃N, (ii) /BRN= 956566/;

DOI:10.1002/jlac.19677090126

upstream raw materials:

2-bromoethylphosphoric acid dichloride

1-stearoyl-2-O-benzyl-rac-glycerol

trimethylamine

2-O-benzylglycerol

Downstream raw materials:

1-stearoyl-sn-glycero-3-phosphocholine

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