N-carbobenzoxy-L-prolyl-L-phenylalanine 3-(carbobenzoxyamino)propylamide

Base Information

Chemical Name:N-carbobenzoxy-L-prolyl-L-phenylalanine 3-(carbobenzoxyamino)propylamide
CAS No.:88105-58-2
Molecular Formula:C₃₃H₃₈N₄O₆
Molecular Weight:586.688
Hs Code.:

Synonyms:N-carbobenzoxy-L-prolyl-L-phenylalanine 3-(carbobenzoxyamino)propylamide

Suppliers and Price of N-carbobenzoxy-L-prolyl-L-phenylalanine 3-(carbobenzoxyamino)propylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-carbobenzoxy-L-prolyl-L-phenylalanine 3-(carbobenzoxyamino)propylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-carbobenzoxy-L-prolyl-L-phenylalanine 3-(carbobenzoxyamino)propylamide

There total 4 articles about N-carbobenzoxy-L-prolyl-L-phenylalanine 3-(carbobenzoxyamino)propylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 17400-34-9
(3-aminopropyl)carbamic acid benzyl ester hydrochloride

: 17350-17-3
(S)-2-[(S)-1-(benzyloxycarbonyl)pyrrolidine-2-carboxamido]-3-phenylpropanoic acid

: 88105-58-2
N-carbobenzoxy-L-prolyl-L-phenylalanine 3-(carbobenzoxyamino)propylamide

Guidance literature:: With N-Ethylmaleimide; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 25 ℃; for 18h; pH 7.0-7.5;
DOI:10.1021/jm00369a017

Reference yield:

: 7524-50-7
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

: 88105-58-2
N-carbobenzoxy-L-prolyl-L-phenylalanine 3-(carbobenzoxyamino)propylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / HOBt, NEM, DCC / tetrahydrofuran / 18 h / 25 °C / pH 7.0-7.5

2: 98 percent / 2.5 N NaOH / methanol / 25 °C

3: 100 percent / HOBt, NEM, DCC / tetrahydrofuran / 18 h / 25 °C / pH 7.0-7.5

With N-Ethylmaleimide; sodium hydroxide; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol;
DOI:10.1021/jm00369a017

Reference yield:

: 23631-72-3
N-carbobenzoxy-L-prolyl-L-phenylalanine methyl ester

: 88105-58-2
N-carbobenzoxy-L-prolyl-L-phenylalanine 3-(carbobenzoxyamino)propylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / 2.5 N NaOH / methanol / 25 °C

2: 100 percent / HOBt, NEM, DCC / tetrahydrofuran / 18 h / 25 °C / pH 7.0-7.5

With N-Ethylmaleimide; sodium hydroxide; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol;
DOI:10.1021/jm00369a017