(2,4,6-Tri-tert-butylphenyl)bis[(trimethylsilyl)ethynyl]phosphane

Base Information

• Chemical Name: (2,4,6-Tri-tert-butylphenyl)bis[(trimethylsilyl)ethynyl]phosphane
• CAS No.: 169697-81-8
• Molecular Formula: C₂₈H₄₇PSi₂
• Molecular Weight: 470.826
• Mol file: 169697-81-8.mol

Synonyms:(2,4,6-Tri-tert-butylphenyl)bis[(trimethylsilyl)ethynyl]phosphane

Chemical Property of (2,4,6-Tri-tert-butylphenyl)bis[(trimethylsilyl)ethynyl]phosphane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2,4,6-Tri-tert-butylphenyl)bis[(trimethylsilyl)ethynyl]phosphane

There total 6 articles about (2,4,6-Tri-tert-butylphenyl)bis[(trimethylsilyl)ethynyl]phosphane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2,4,6-tri-t-butylphenylphosphonous dichloride (79074-00-3) + trimethylsilylacetylene (1066-54-2) → (2,4,6-Tri-tert-butylphenyl)bis[(trimethylsilyl)ethynyl]phosphane (169697-81-8)

Guidance literature:

trimethylsilylacetylene; With n-butyllithium; In diethyl ether; at -50 ℃; for 0.5h;

2,4,6-tri-t-butylphenylphosphonous dichloride; In diethyl ether; at -78 - 20 ℃; for 12h;

DOI:10.1002/1521-3765(20001016)6:20<3806::AID-CHEM3806>3.0.CO;2-J

Reference yield:

chloro-trimethyl-silane (75-77-4) + Diethynyl(2,4,6-tri-tert-butylphenyl)phosphane (169697-84-1) → ethynyl(2,4,6-tri-t-butylphenyl)(trimethylsilylethynyl)phosphine + (2,4,6-Tri-tert-butylphenyl)bis[(trimethylsilyl)ethynyl]phosphane (169697-81-8)

Guidance literature:

Diethynyl(2,4,6-tri-tert-butylphenyl)phosphane; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃;

chloro-trimethyl-silane; In tetrahydrofuran; hexane; at 20 ℃; Title compound not separated from byproducts;

DOI:10.1002/1521-3765(20001016)6:20<3806::AID-CHEM3806>3.0.CO;2-J

Reference yield:

Diethynyl(2,4,6-tri-tert-butylphenyl)phosphane (169697-84-1) → (2,4,6-Tri-tert-butylphenyl)bis[(trimethylsilyl)ethynyl]phosphane (169697-81-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: BuLi / tetrahydrofuran; hexane / 1 h / -78 °C

1.2: 13 percent / tetrahydrofuran; hexane / 3 h / 20 °C

2.1: 16 percent / TBAF / tetrahydrofuran / 3 h / -78 °C

3.1: BuLi / tetrahydrofuran; hexane / -78 °C

3.2: tetrahydrofuran; hexane / 20 °C

With n-butyllithium; tetrabutyl ammonium fluoride; In tetrahydrofuran; hexane; 1.1: Metallation / 1.2: Substitution / 2.1: Desilylation / 3.1: Metallation / 3.2: Substitution;

DOI:10.1002/1521-3765(20001016)6:20<3806::AID-CHEM3806>3.0.CO;2-J

upstream raw materials:

n-butyllithium

2,4,6-tri-t-butylphenylphosphonous dichloride

trimethylsilylacetylene

chloro-trimethyl-silane

Downstream raw materials:

(2,4,6-Tri-tert-butylphenyl)bis({(2,4,6-tri-tert-butylphenyl)[(triisopropylsilyl)ethynyl]phosphanyl}butdiynyl)phosphane

(2,4,6-Tri-tert-butylphenyl)bis{[ethynyl(2,4,6-tri-tert-butylphenyl)phosphanyl]butadiynyl}phosphane

Bis{(2,4,6-tert-butylphenyl)[(triisopropylsilyl)ethynyl]phosphanyl}butadiyne

[Ethynyl(2,4,6-tri-tert-butylphenyl)phosphanyl]{2,4,6-tri-tert-butylphenyl[(triisopropylsilyl)ethynyl]phosphanyl}butdiyne