1-(Diphenylphosphanyl)-2,2-bis<(diphenylphosphanyl)methyl>-3-phenylpropan

Base Information

• Chemical Name: 1-(Diphenylphosphanyl)-2,2-bis<(diphenylphosphanyl)methyl>-3-phenylpropan
• CAS No.: 153175-09-8
• Molecular Formula: C₄₇H₄₃P₃
• Molecular Weight: 700.78
• Mol file: 153175-09-8.mol

Synonyms:1-(Diphenylphosphanyl)-2,2-bis<(diphenylphosphanyl)methyl>-3-phenylpropan

Chemical Property of 1-(Diphenylphosphanyl)-2,2-bis<(diphenylphosphanyl)methyl>-3-phenylpropan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(Diphenylphosphanyl)-2,2-bis<(diphenylphosphanyl)methyl>-3-phenylpropan

There total 2 articles about 1-(Diphenylphosphanyl)-2,2-bis<(diphenylphosphanyl)methyl>-3-phenylpropan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

(3-Chloro-2,2-bis-chloromethyl-propyl)-benzene (160820-68-8) + diphenylphosphane (829-85-6) → 1-(Diphenylphosphanyl)-2,2-bis<(diphenylphosphanyl)methyl>-3-phenylpropan (153175-09-8)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; for 16h; Heating;

DOI:10.1016/j.tet.2007.03.076

Reference yield:

2-benzyl-2-(hydroxymethyl)propane-1,3-diol (67590-35-6) → 1-(Diphenylphosphanyl)-2,2-bis<(diphenylphosphanyl)methyl>-3-phenylpropan (153175-09-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 53 percent / pyridine; thionyl chloride / 6 h / 0 - 115 °C

2: 63 percent / potassium tert-butoxide / tetrahydrofuran / 16 h / Heating

With pyridine; thionyl chloride; potassium tert-butylate; In tetrahydrofuran;

DOI:10.1016/j.tet.2007.03.076

Reference yield: 98.0%

di-μ-chloro-bis(1,5-cyclooctadiene)dirhodium (12092-47-6) + sodium tetraphenyl borate (143-66-8) + 1-(Diphenylphosphanyl)-2,2-bis<(diphenylphosphanyl)methyl>-3-phenylpropan (153175-09-8) → (η(4)-1,5-cycloctadiene)[2-phenyl-1,1,1,-tris(diphenylphosphanylmethyl)ethane]rhodium(I) tetraphenylborate

Guidance literature:

In dichloromethane; acetone; byproducts: NaCl; (N2); stirring (10 min); solvent removal, addn. of CH2Cl2, centrifugation, concn., pptn. with Et2O; elem. anal.;

upstream raw materials:

(3-Chloro-2,2-bis-chloromethyl-propyl)-benzene

diphenylphosphane

2-benzyl-2-(hydroxymethyl)propane-1,3-diol

Downstream raw materials:

[η(3)-1-(diphenylphosphanyl)-2,2-bis[(diphenylphosphanyl)methyl]-3-phenylpropane]NiCl