Technology Process of C34H51NO7Si
There total 5 articles about C34H51NO7Si which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(3R)-3-propionyl-4-benzyloxazolidin-2-one;
With
titanium tetrachloride;
In
dichloromethane;
at 0 ℃;
Inert atmosphere;
With
(1R,2R,9R)-11-methyl-7,11-diazatricyclo[7.3.1.02,7]tridecane;
In
dichloromethane;
at 0 ℃;
for 0.333333h;
Inert atmosphere;
(3S)-3-tert-butyldimethylsilyloxy-5-p-methoxybenzyloxy-2,2-dimethylpentanal;
at -78 - 0 ℃;
for 3h;
DOI:10.1021/ol303089w
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium borohydride / diethyl ether; water / 3.5 h / 0 - 23 °C / Inert atmosphere
2.1: N-ethyl-N,N-diisopropylamine; dimethyl sulfoxide / dichloromethane / 0.08 h / -20 - -10 °C / Inert atmosphere
2.2: 2 h / -20 - -10 °C / Inert atmosphere
3.1: titanium tetrachloride / dichloromethane / 0 °C / Inert atmosphere
3.2: 0.33 h / 0 °C / Inert atmosphere
3.3: 3 h / -78 - 0 °C
With
lithium borohydride; titanium tetrachloride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine;
In
diethyl ether; dichloromethane; water;
2.2: |Parikh-Doering Oxidation / 3.3: |Evans Aldol Reaction;
DOI:10.1021/ol303089w
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: N-ethyl-N,N-diisopropylamine; dimethyl sulfoxide / dichloromethane / 0.08 h / -20 - -10 °C / Inert atmosphere
1.2: 2 h / -20 - -10 °C / Inert atmosphere
2.1: titanium tetrachloride / dichloromethane / 0 °C / Inert atmosphere
2.2: 0.33 h / 0 °C / Inert atmosphere
2.3: 3 h / -78 - 0 °C
With
titanium tetrachloride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
1.2: |Parikh-Doering Oxidation / 2.3: |Evans Aldol Reaction;
DOI:10.1021/ol303089w
