472979-90-1

Upstream product

• 472979-84-3 3-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,2-dimethyl-pentanoic acid methyl ester 
• 128461-65-4 3-(p-methoxybenzyloxy)propanal 
• 1416328-50-1 C₂₅H₃₁NO₆ 
• 1416328-61-4 C₃₁H₄₅NO₆Si 
• 472979-31-0 (S)-3-hydroxy-5-(4-methoxybenzyloxy)-2,2-dimethylpentanoic acid methyl ester 

Downstream Products

• 472979-36-5 (3S)-3-tert-butyldimethylsilyloxy-5-p-methoxybenzyloxy-2,2-dimethylpentanal 
• 1416328-51-2 C₃₄H₅₁NO₇Si 
• 1416328-62-5 C₃₇H₅₉NO₇Si₂ 
• 1416328-52-3 C₂₇H₅₂O₅Si₂ 
• 1416328-49-8 C₂₇H₅₀O₅Si₂ 
• 1416328-54-5 C₂₈H₄₀O₅ 
• 1416328-71-6 C₂₄H₄₄O₅Si 
• 1416328-55-6 C₂₇H₄₈O₅Si 
• 472979-51-4 1-[3-(tert-butyl-dimethyl-silanyloxy)-4,4-dimethyl-5-(2-trimethylsilanyl-ethoxymethoxy)-oct-6-enyloxymethyl]-4-methoxy-benzene 
• 472979-46-7 6-(tert-butyl-dimethyl-silanyloxy)-8-(4-methoxy-benzyloxy)-5,5-dimethyl-oct-2-en-4-ol 

Relevant academic research and scientific papers

Enantioselective synthesis of the C(1)-C(11) fragment of tedanolide C

A convergent synthesis of the protected C(1)-C(11) fragment 6 of the targeted enantiomer of tedanolide C is described. The key step of the synthesis is the Felkin-Ahn addition of vinyl iodide 7 to aldehyde 8 that proceeds in 80% yield with 4:1 diastereose

Toward the total synthesis of disorazole A(1) and C(1): asymmetric synthesis of a masked southern segment.

[reaction: see text] A highly convergent asymmetric synthesis of the masked southern segment of the antimitotic agent disorazole A(1) involves a Sonogashira coupling between a C1'-C10' enyne and a suitably protected C11'-C19' vinyl iodide. The central E,Z,Z-triene moiety is masked as a more stable ynediene.