diethyl 1-benzoylpentylphosphonate

Base Information

• Chemical Name: diethyl 1-benzoylpentylphosphonate
• CAS No.: 1149803-68-8
• Molecular Formula: C₁₆H₂₅O₄P
• Molecular Weight: 312.346
• Mol file: 1149803-68-8.mol

Synonyms:diethyl 1-benzoylpentylphosphonate

Chemical Property of diethyl 1-benzoylpentylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of diethyl 1-benzoylpentylphosphonate

There total 2 articles about diethyl 1-benzoylpentylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

C17H38BO3P (1013636-17-3) + benzoyl chloride (98-88-4) → diethyl 1-benzoylpentylphosphonate (1149803-68-8) + benzoic acid 2-(diethoxy-phosphoryl)-phenyl-hex-1-enyl ester

Guidance literature:

C₁₇H₃₈BO₃P; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; Inert atmosphere;

benzoyl chloride; In tetrahydrofuran; hexane; at -78 ℃; Inert atmosphere; Reflux;

DOI:10.1021/jo900300c

Reference yield: 30.0%

diethyl chloromethylphosphonate (3167-63-3) + tributyl borane (122-56-5) + benzoyl chloride (98-88-4) → diethyl pentylphosphonate (1186-17-0) + diethyl 1-benzoylpentylphosphonate (1149803-68-8) + benzoic acid 2-(diethoxy-phosphoryl)-phenyl-hex-1-enyl ester

Guidance literature:

diethyl chloromethylphosphonate; With n-butyllithium; In tetrahydrofuran; at -90 ℃; Inert atmosphere;

tributyl borane; In tetrahydrofuran; diethyl ether; at -90 - 20 ℃; Inert atmosphere;

benzoyl chloride; Further stages;

DOI:10.1021/jo900300c

upstream raw materials:

C₁₇H₃₈BO₃P

benzoyl chloride

diethyl chloromethylphosphonate

tributyl borane

Refernces