O-(1-(4-(azidomethyl)phenyl)ethyl)-N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)hydroxylamine

Base Information

• Chemical Name: O-(1-(4-(azidomethyl)phenyl)ethyl)-N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)hydroxylamine
• CAS No.: 393110-71-9
• Molecular Formula: C₂₃H₃₂N₄O
• Molecular Weight: 380.533
• Mol file: 393110-71-9.mol

Synonyms:O-(1-(4-(azidomethyl)phenyl)ethyl)-N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)hydroxylamine

Chemical Property of O-(1-(4-(azidomethyl)phenyl)ethyl)-N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)hydroxylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-(1-(4-(azidomethyl)phenyl)ethyl)-N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)hydroxylamine

There total 1 articles about O-(1-(4-(azidomethyl)phenyl)ethyl)-N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.4%

N-tert-butyl-O-[1-(4-chloromethyl-phenyl)-ethyl]-N-(2-methyl-1-phenyl-propyl)-hydroxylamine (227000-85-3) → O-(1-(4-(azidomethyl)phenyl)ethyl)-N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)hydroxylamine (393110-71-9)

Guidance literature:

With sodium azide; 18-crown-6 ether; In dimethyl sulfoxide; at 60 ℃; for 16h;

DOI:10.1021/ja028392s

Reference yield: 91.0%

O-(1-(4-(azidomethyl)phenyl)ethyl)-N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)hydroxylamine (393110-71-9) → 2,2,5-trimethyl-3-(1'-p-aminomethylphenylethoxy)-4-phenyl-3-azahexane (293328-23-1)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 16h;

DOI:10.1021/ja028392s

Reference yield: 78.0%

tripopargylamine (6921-29-5) + O-(1-(4-(azidomethyl)phenyl)ethyl)-N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)hydroxylamine (393110-71-9) → tris((1-(4-(1-((tert-butyl(2-methyl-1-phenylpropyl)amino)oxy)ethyl)benzyl)-1H-1,2,3-triazol-4-yl)methyl)amine (1616758-34-9)

Guidance literature:

With copper(l) iodide; In tetrahydrofuran; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1039/c4cc03370a

upstream raw materials:

N-tert-butyl-O-[1-(4-chloromethyl-phenyl)-ethyl]-N-(2-methyl-1-phenyl-propyl)-hydroxylamine

Downstream raw materials:

2,2,5-trimethyl-3-(1'-p-aminomethylphenylethoxy)-4-phenyl-3-azahexane

2,2,5-trimethyl-3-(1'-p-(t-butyloxycarbonylamino)methylphenylethoxy)-4-phenyl-3-azahexane

tris((1-(4-(1-((tert-butyl(2-methyl-1-phenylpropyl)amino)oxy)ethyl)benzyl)-1H-1,2,3-triazol-4-yl)methyl)amine