3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶,2'-O-bis[2-(4-nitrophenyl)ethoxycarbonyl]a...

Base Information

• Chemical Name: 3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶,2'-O-bis[2-(4-nitrophenyl)ethoxycarbonyl]a...
• CAS No.: 168772-71-2
• Molecular Formula: C₈₂H₇₉N₂₁O₃₃P₂
• Molecular Weight: 1948.6
• Mol file: 168772-71-2.mol

Synonyms:3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶,2'-O-bis[2-(4-nitrophenyl)ethoxycarbonyl]a...

Chemical Property of 3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶,2'-O-bis[2-(4-nitrophenyl)ethoxycarbonyl]a...

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶,2'-O-bis[2-(4-nitrophenyl)ethoxycarbonyl]a...

There total 1 articles about 3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶,2'-O-bis[2-(4-nitrophenyl)ethoxycarbonyl]a... which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3'-deoxy-5'-O-(monomethoxytrityl)-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N6,2'-O-bis<2-(4-nit... (97777-00-9) → 3'-deoxy-N6-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{OP-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N6-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{OP-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N6,2'-O-bis[2-(4-nitrophenyl)ethoxycarbonyl]a... (168772-71-2)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; dichloromethane;

DOI:10.1080/15257779508012544

Reference yield: 79.0%

6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}hexanoic acid (88574-06-5) + 3'-deoxy-N6-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{OP-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N6-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{OP-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N6,2'-O-bis[2-(4-nitrophenyl)ethoxycarbonyl]a... (168772-71-2) → 3'-deoxy-5'-O-[6-({[(9H-fluorenyl-9-yl)methoxy]carbonyl}amino)hexanoyl]-N6-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{OP-[2-(4-nitrophenyl)ethyl]}[*]5')-3'-deoxy-N6-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{OP-[2-(4-nitrophenyl)...]})

Guidance literature:

With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane; for 5.5h; Ambient temperature;

DOI:10.1002/hlca.19970800405

Reference yield:

succinic acid anhydride (108-30-5) + 1,2-dihexadecylglycerol (6076-35-3) + 3'-deoxy-N6-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{OP-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N6-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{OP-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N6,2'-O-bis[2-(4-nitrophenyl)ethoxycarbonyl]a... (168772-71-2) → 3'-deoxy-5'-O-{[2-(2,3-di-O-hexadecylglycer-1-yloxycarbonyl)ethyl]carbonyl}-N6-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{OP-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N6-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-[2'-[OP-[2-(4-nitrophenyl)et...

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; Yield given. Multistep reaction; 1.) CH₂Cl₂, 19 h; 2.) CH₂Cl₂, 6 h + 15 h with DMAP;

DOI:10.1002/hlca.19960790305

upstream raw materials:

3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶,2'-O-bis<2-(4-nit...