(R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine

Base Information

Chemical Name:(R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
CAS No.:193686-74-7
Molecular Formula:C₁₉H₂₀ClNO₄S
Molecular Weight:393.891
Hs Code.:

Synonyms:(R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine

Suppliers and Price of (R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine

Chemical Property:

Purity/Quality:: 98% HPLC ^*data from raw suppliers

Safty Information:

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Hazard Codes:

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Technology Process of (R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine

There total 1 articles about (R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

: 108-05-4,9003-20-7
vinyl acetate

: 7-chloro-5-hydroxy-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine

: 193686-74-7
(R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine

Guidance literature:: With Lipozyme IM; at 38 ℃; for 48h;
DOI:10.3987/COM-99-S(I)2

Reference yield: 70.0%

: 193686-74-7
(R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine

: 193686-75-8
(R)-7-chloro-5-hydroxy-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine

Guidance literature:: With potassium carbonate; In methanol; at 20 ℃; for 0.5h;
DOI:10.3987/COM-99-S(I)2

Reference yield:

: 193686-74-7
(R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine

: 331947-59-2
(R)-7-chloro-5-methoxymethyloxy-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine

Guidance literature:: Multi-step reaction with 2 steps

1.1: 70 percent / K₂CO₃ / methanol / 0.5 h / 20 °C

2.1: NaH / dimethylformamide / 0.5 h

2.2: dimethylformamide / 18 h / 20 °C

With sodium hydride; potassium carbonate; In methanol; N,N-dimethyl-formamide;
DOI:10.3987/COM-99-S(I)2