Dimethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate

Base Information

Chemical Name:Dimethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate
CAS No.:17438-14-1
Molecular Formula:C11H15 N O4
Molecular Weight:225.244
Hs Code.:2933399090
European Community (EC) Number:241-458-3
DSSTox Substance ID:DTXSID20169820
Nikkaji Number:J287.052E
Mol file:17438-14-1.mol

Synonyms:17438-14-1;Dimethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;Dimethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate;EINECS 241-458-3;3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-, 3,5-dimethyl ester;Maybridge4_001804;Oprea1_491268;SCHEMBL3295915;DTXSID20169820;HMS1526B22;3,5-dimethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;AKOS000313772;CCG-251387;NCGC00177241-01;SR-01000027613;SR-01000027613-1;BRD-K72177560-001-01-4;Dimethyl2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;Dimethyl 2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate #;Methyl (2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate);1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid dimethyl ester;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-, dimethyl ester;2,6-DIMETHYL-1,4-DIHYDRO-PYRIDINE-3,5-DICARBOXYLIC ACID DIMETHYL ESTER

Suppliers and Price of Dimethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Dimethyl2,6-Dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
5g
$ 500.00

Total 5 raw suppliers

Chemical Property of Dimethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate

Chemical Property:

Vapor Pressure:0.000289mmHg at 25°C
Boiling Point:321.9°Cat760mmHg
Flash Point:148.5°C
PSA：64.63000
Density:1.147g/cm³
LogP:1.20250
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:225.10010796
Heavy Atom Count:16
Complexity:357

Purity/Quality:

99% ^*data from raw suppliers

Dimethyl2,6-Dimethyl-1,4-dihydropyridine-3,5-dicarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1=C(CC(=C(N1)C)C(=O)OC)C(=O)OC
Uses Dimethyl 2,6-Dimethyl-1,4-dihydropyridine-3,5-dicarboxylate is used in method for synthesizing 3,4-dihydropyrimidinone compound by asymmetric transfer hydrogenation.

Technology Process of Dimethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate

There total 7 articles about Dimethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 105-45-3
acetoacetic acid methyl ester

: 17438-14-1
2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine

Guidance literature:: With ammonium acetate; sodium dodecyl-sulfate; toluene-4-sulfonic acid; for 1h; ultrasonic irradiation;
DOI:10.1055/s-2008-1042908

Reference yield: 76.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: ammonium acetoacetate

: 105-45-3
acetoacetic acid methyl ester

: 17438-14-1
2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine

Guidance literature:: In methanol; at 70 ℃; for 0.25h;
DOI:10.1016/j.tetlet.2019.151129

Reference yield: 68.0%

: 124-38-9,18923-20-1
carbon dioxide

: 105-45-3
acetoacetic acid methyl ester

: 17438-14-1
2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine

Guidance literature:: With potassium tert-butylate; ammonium chloride; ethanolamine; Selectfluor; In water; at 120 ℃; for 24h; Sealed tube; Green chemistry;
DOI:10.1039/d1gc02303a