C-(2-METHOXY-PHENYL)-C-PHENYL-METHYLAMINE

Base Information

• Chemical Name: C-(2-METHOXY-PHENYL)-C-PHENYL-METHYLAMINE
• CAS No.: 55095-19-7
• Molecular Formula: C₁₄H₁₅NO
• Molecular Weight: 213.279
• Mol file: 55095-19-7.mol

Synonyms:2-methoxy-benzhydrylamine

Chemical Property of C-(2-METHOXY-PHENYL)-C-PHENYL-METHYLAMINE

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C-(2-METHOXY-PHENYL)-C-PHENYL-METHYLAMINE

There total 7 articles about C-(2-METHOXY-PHENYL)-C-PHENYL-METHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-bromoanisole (578-57-4) + benzonitrile (100-47-0) → 2-methoxy-benzhydrylamine (55095-19-7)

Guidance literature:

2-bromoanisole; benzonitrile; With bis(cyclopentadienyl)titanium dichloride; chloro-trimethyl-silane; [nickel(II)dichloride(dimethoxyethane)]; 4,4'-di-tert-butyl-2,2'-bipyridine; zinc; In 1,4-dioxane; at 60 ℃; for 24h;

With sodium tetrahydroborate; chemoselective reaction;

DOI:10.1021/acscatal.8b00244

Reference yield:

2-methoxy-benzophenone-seqcis-oxime (23997-78-6) → 2-methoxy-benzhydrylamine (55095-19-7)

Guidance literature:

With ethanol; sodium;

Reference yield:

(2-methoxyphenyl)phenylmethanone oxime (23997-78-6) → 2-methoxy-benzhydrylamine (55095-19-7)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / beim Umkristallisieren

2: sodium; alcohol

With ethanol; sodium; acetic acid;

upstream raw materials:

2-methoxy-benzophenone-seqcis-oxime

ethanol

(2-methoxyphenyl)phenylmethanone oxime

ortho-methoxybenzophenone

Refernces