diethyl [3,5-dimethyl-4-(4'-methoxymethoxy-3'-iso-propylbenzyl)phenoxy]methylphosphonate

Base Information

Chemical Name:diethyl [3,5-dimethyl-4-(4'-methoxymethoxy-3'-iso-propylbenzyl)phenoxy]methylphosphonate
CAS No.:852947-40-1
Molecular Formula:C₂₅H₃₇O₆P
Molecular Weight:464.539
Hs Code.:

Synonyms:diethyl [3,5-dimethyl-4-(4'-methoxymethoxy-3'-iso-propylbenzyl)phenoxy]methylphosphonate

Suppliers and Price of diethyl [3,5-dimethyl-4-(4'-methoxymethoxy-3'-iso-propylbenzyl)phenoxy]methylphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of diethyl [3,5-dimethyl-4-(4'-methoxymethoxy-3'-iso-propylbenzyl)phenoxy]methylphosphonate

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of diethyl [3,5-dimethyl-4-(4'-methoxymethoxy-3'-iso-propylbenzyl)phenoxy]methylphosphonate

There total 11 articles about diethyl [3,5-dimethyl-4-(4'-methoxymethoxy-3'-iso-propylbenzyl)phenoxy]methylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 60682-95-3
1-(diethoxyphosphorylmethylsulfonyl)-4-methylbenzene

: 328236-47-1
3,5-dimethyl-4-(3'-isopropyl-4'-O-methoxymethylbenzyl)phenol

: 852947-40-1
diethyl [3,5-dimethyl-4-(4'-methoxymethoxy-3'-iso-propylbenzyl)phenoxy]methylphosphonate

Guidance literature:: 3,5-dimethyl-4-(3'-isopropyl-4'-O-methoxymethylbenzyl)phenol; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

1-(diethoxyphosphorylmethylsulfonyl)-4-methylbenzene; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 16h;

Reference yield: 64.0%

: 31618-90-3
diethyl (p-toluenesulfonyloxymethane)phosphonate

: 328236-47-1
3,5-dimethyl-4-(3'-isopropyl-4'-O-methoxymethylbenzyl)phenol

: 852947-40-1
diethyl [3,5-dimethyl-4-(4'-methoxymethoxy-3'-iso-propylbenzyl)phenoxy]methylphosphonate

Guidance literature:: 3,5-dimethyl-4-(3'-isopropyl-4'-O-methoxymethylbenzyl)phenol; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1h;

diethyl (p-toluenesulfonyloxymethane)phosphonate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 16h; Product distribution / selectivity;

Reference yield:

: 328236-44-8
2,6-dimethyl-4-(triisopropyl-silanyloxy)-benzaldehyde

: 852947-40-1
diethyl [3,5-dimethyl-4-(4'-methoxymethoxy-3'-iso-propylbenzyl)phenoxy]methylphosphonate

Guidance literature:: Multi-step reaction with 4 steps

1.1: n-butyllithium / tetrahydrofuran / 1.75 h / -75 - -70 °C

1.2: 3 h / -75 - -70 °C

2.1: hydrogen / palladium 10% on activated carbon / acetic acid; ethyl acetate / 3 h / 20 °C

3.1: tetraethylammonium fluoride / tetrahydrofuran / 1 h / 20 °C

3.2: 0.25 h

4.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 20 °C

4.2: 16 h / 0 - 20 °C

With n-butyllithium; hydrogen; sodium hydride; tetraethylammonium fluoride; palladium 10% on activated carbon; In tetrahydrofuran; acetic acid; ethyl acetate; N,N-dimethyl-formamide;