C₄₇H₆₄O₁₃Si₂

Base Information

• Chemical Name: C₄₇H₆₄O₁₃Si₂
• CAS No.: 1313275-65-8
• Molecular Formula: C₄₇H₆₄O₁₃Si₂
• Molecular Weight: 893.188
• Mol file: 1313275-65-8.mol

Synonyms:C₄₇H₆₄O₁₃Si₂

Chemical Property of C₄₇H₆₄O₁₃Si₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₇H₆₄O₁₃Si₂

There total 35 articles about C₄₇H₆₄O₁₃Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1-diazo-3-epoxy-5,5-dimethoxypenta-2,4-dione (1313275-02-3) + C39H54O8Si2 (1313275-00-1) → C47H64O13Si2 (1313275-26-1) + C47H64O13Si2 (1313275-65-8) + C47H64O13Si2 (1313275-63-6) + KCN-Triox1 (1313274-97-3)

Guidance literature:

dirhodium tetraacetate; In dichloromethane; at 23 ℃; for 0.166667h; Molecular sieve;

Reference yield:

methyl 2-(allyloxy)-4-methylbenzoate → C47H64O13Si2 (1313275-26-1) + C47H64O13Si2 (1313275-65-8) + C47H64O13Si2 (1313275-63-6) + KCN-Triox1 (1313274-97-3)

Guidance literature:

Multi-step reaction with 11 steps

1.1: trimethylaluminum / toluene / 0.17 h / 0 °C

1.2: 7.75 h / 23 °C / Reflux

2.1: 13 h / 220 °C / Neat (no solvent)

3.1: potassium tert-butylate / dimethyl sulfoxide / 1.17 h / 23 - 120 °C

4.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / 23 °C

5.1: N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium / tetrahydrofuran / 1 h / -78 °C

5.2: 17.5 h / -78 - 23 °C

5.3: 0.33 h / 23 °C

6.1: dichloromethane / 1.25 h / 0 - 23 °C

6.2: 40 h / 23 °C

7.1: lithium tert-butoxide / tetrahydrofuran / 0.08 h / -78 °C

7.2: 2.5 h / -78 - -22 °C

7.3: 4.5 h / -22 - 23 °C

8.1: 2,6-dimethylpyridine; sodium periodate; potassium osmate(VI) dihydrate / water; tetrahydrofuran / 2 h / 0 - 23 °C

9.1: bromocatecholborane / dichloromethane / 0.75 h / -78 °C

9.2: -78 - 23 °C

10.1: N-ethyl-N,N-diisopropylamine; benzotriazol-1-ol / N,N-dimethyl-formamide / 1.33 h / 23 - 55 °C

11.1: tetrakis(actonitrile)copper(I) hexafluorophosphate / dichloromethane / 2.67 h / 23 °C / Molecular sieve

With 2,6-dimethylpyridine; potassium osmate(VI) dihydrate; sodium periodate; N,N,N,N,-tetramethylethylenediamine; bromocatecholborane; potassium tert-butylate; trimethylaluminum; tert.-butyl lithium; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; lithium tert-butoxide; tetrakis(actonitrile)copper(I) hexafluorophosphate; In tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene;

Reference yield:

methyl 2-hydroxy-4-methylbenzoate (4670-56-8) → C47H64O13Si2 (1313275-26-1) + C47H64O13Si2 (1313275-65-8) + C47H64O13Si2 (1313275-63-6) + KCN-Triox1 (1313274-97-3)

Guidance literature:

Multi-step reaction with 12 steps

1.1: sodium hydride; phenol / N,N-dimethyl-formamide / 6 h / 0 - 23 °C

2.1: trimethylaluminum / toluene / 0.17 h / 0 °C

2.2: 7.75 h / 23 °C / Reflux

3.1: 13 h / 220 °C / Neat (no solvent)

4.1: potassium tert-butylate / dimethyl sulfoxide / 1.17 h / 23 - 120 °C

5.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / 23 °C

6.1: N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium / tetrahydrofuran / 1 h / -78 °C

6.2: 17.5 h / -78 - 23 °C

6.3: 0.33 h / 23 °C

7.1: dichloromethane / 1.25 h / 0 - 23 °C

7.2: 40 h / 23 °C

8.1: lithium tert-butoxide / tetrahydrofuran / 0.08 h / -78 °C

8.2: 2.5 h / -78 - -22 °C

8.3: 4.5 h / -22 - 23 °C

9.1: 2,6-dimethylpyridine; sodium periodate; potassium osmate(VI) dihydrate / water; tetrahydrofuran / 2 h / 0 - 23 °C

10.1: bromocatecholborane / dichloromethane / 0.75 h / -78 °C

10.2: -78 - 23 °C

11.1: N-ethyl-N,N-diisopropylamine; benzotriazol-1-ol / N,N-dimethyl-formamide / 1.33 h / 23 - 55 °C

12.1: tetrakis(actonitrile)copper(I) hexafluorophosphate / dichloromethane / 2.67 h / 23 °C / Molecular sieve

With 2,6-dimethylpyridine; potassium osmate(VI) dihydrate; sodium periodate; N,N,N,N,-tetramethylethylenediamine; bromocatecholborane; potassium tert-butylate; trimethylaluminum; tert.-butyl lithium; sodium hydride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; lithium tert-butoxide; phenol; tetrakis(actonitrile)copper(I) hexafluorophosphate; In tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene;

upstream raw materials:

tert-butyldimethylsilyl chloride

2-hydroxy-p-toluic acid

methyl 2-hydroxy-4-methylbenzoate

(3S)-3-[(1,1-Dimethylethyl)dimethylsilyloxy]-oxolan-2-one