5-[methyl(phenyl)amino]-2-(4-nitrobenzyl)-3-p-tolyl-1,2,4-thiadiazolium perchlorate

Base Information

• Chemical Name: 5-[methyl(phenyl)amino]-2-(4-nitrobenzyl)-3-p-tolyl-1,2,4-thiadiazolium perchlorate
• CAS No.: 1264264-01-8
• Molecular Formula: C₂₃H₂₁N₄O₂S*ClO₄
• Molecular Weight: 516.962
• Mol file: 1264264-01-8.mol

Synonyms:5-[methyl(phenyl)amino]-2-(4-nitrobenzyl)-3-p-tolyl-1,2,4-thiadiazolium perchlorate

Chemical Property of 5-[methyl(phenyl)amino]-2-(4-nitrobenzyl)-3-p-tolyl-1,2,4-thiadiazolium perchlorate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-[methyl(phenyl)amino]-2-(4-nitrobenzyl)-3-p-tolyl-1,2,4-thiadiazolium perchlorate

There total 1 articles about 5-[methyl(phenyl)amino]-2-(4-nitrobenzyl)-3-p-tolyl-1,2,4-thiadiazolium perchlorate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1-Methyl-3-{[(E)-4-nitro-benzylimino]-p-tolyl-methyl}-1-phenyl-thiourea (212254-00-7) → 5-[methyl(phenyl)amino]-2-(4-nitrobenzyl)-3-p-tolyl-1,2,4-thiadiazolium perchlorate (1264264-01-8)

Guidance literature:

1-Methyl-3-{[(E)-4-nitro-benzylimino]-p-tolyl-methyl}-1-phenyl-thiourea; With pyridine; bromine; In dichloromethane;

With sodium perchlorate; In ethanol; water;

DOI:10.1134/S107036321110032X

Reference yield: 86.0%

5-[methyl(phenyl)amino]-2-(4-nitrobenzyl)-3-p-tolyl-1,2,4-thiadiazolium perchlorate (1264264-01-8) → 4-methyl-N-[3-methyl-1,3-benzothiazol-2(3H)-ylidene]-N'-(4-nitrobenzyl)benzenecarboximidamide perchlorate (1352569-82-4)

Guidance literature:

at 190 ℃; for 0.666667h;

DOI:10.1134/S107036321110032X

Reference yield:

5-[methyl(phenyl)amino]-2-(4-nitrobenzyl)-3-p-tolyl-1,2,4-thiadiazolium perchlorate (1264264-01-8) → 4-methyl-N-[3-methyl-1,3-benzothiazol-2(3H)-ylidene]-N'-(4-nitrobenzyl)benzenecarboximidamide (670255-01-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.67 h / 190 °C

2: triethylamine / tetrahydrofuran / 4 h

With triethylamine; In tetrahydrofuran;

DOI:10.1134/S107036321110032X

upstream raw materials:

1-Methyl-3-{[(E)-4-nitro-benzylimino]-p-tolyl-methyl}-1-phenyl-thiourea

Downstream raw materials:

4-methyl-N-[3-methyl-1,3-benzothiazol-2(3H)-ylidene]-N'-(4-nitrobenzyl)benzenecarboximidamide perchlorate

4-methyl-N-[3-methyl-1,3-benzothiazol-2(3H)-ylidene]-N'-(4-nitrobenzyl)benzenecarboximidamide

9-methyl-3a-(4-nitrophenyl)-2-p-tolyl-3a,9-dihydrobenzo[b]imidazo[4,5-e]-1,4-thiazine