2-phenyl-4,5-dihydro-1,3-oxazole-4,5,5-tricarboxylic acid triethyl ester

Base Information

Chemical Name:2-phenyl-4,5-dihydro-1,3-oxazole-4,5,5-tricarboxylic acid triethyl ester
CAS No.:125422-65-3
Molecular Formula:C₁₈H₂₁NO₇
Molecular Weight:363.367
Hs Code.:

Synonyms:2-phenyl-4,5-dihydro-1,3-oxazole-4,5,5-tricarboxylic acid triethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-phenyl-4,5-dihydro-1,3-oxazole-4,5,5-tricarboxylic acid triethyl ester

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Technology Process of 2-phenyl-4,5-dihydro-1,3-oxazole-4,5,5-tricarboxylic acid triethyl ester

There total 2 articles about 2-phenyl-4,5-dihydro-1,3-oxazole-4,5,5-tricarboxylic acid triethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 25755-93-5
5-ethoxy-2-phenyl-1,3-oxazole

: 609-09-6
Diethyl ketomalonate

: 125422-65-3
2-phenyl-4,5-dihydro-1,3-oxazole-4,5,5-tricarboxylic acid triethyl ester

Guidance literature:: With tin(IV) chloride; In acetonitrile; for 19h; Ambient temperature;
DOI:10.1246/cl.1994.1673

Reference yield:

: 25755-93-5
5-ethoxy-2-phenyl-1,3-oxazole

: 609-09-6
Diethyl ketomalonate

: 125422-64-2
2,5,5-tricarbethoxy-4-phenyl-3-oxazoline

: 125422-65-3
2-phenyl-4,5-dihydro-1,3-oxazole-4,5,5-tricarboxylic acid triethyl ester

Guidance literature:: In xylene; for 46h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;
DOI:10.1016/S0040-4020(01)81032-2