3-(ALLYLOXY)-4,5,6-TRIS(BENZYLOXY)-2-([TERT-BUTYL(DIMETHYL)SILYL]OXY)CYCLOHEXANOL

Base Information

Chemical Name:3-(ALLYLOXY)-4,5,6-TRIS(BENZYLOXY)-2-([TERT-BUTYL(DIMETHYL)SILYL]OXY)CYCLOHEXANOL
CAS No.:136282-33-2
Molecular Formula:C₃₆H₄₈O₆Si
Molecular Weight:604.859
Hs Code.:
Mol file:136282-33-2.mol

Synonyms:4-O-allyl-1,5,6-tri-O-benzyl-3-O-tert-butyldimethylsilyl-myo-inositol

Suppliers and Price of 3-(ALLYLOXY)-4,5,6-TRIS(BENZYLOXY)-2-([TERT-BUTYL(DIMETHYL)SILYL]OXY)CYCLOHEXANOL

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(ALLYLOXY)-4,5,6-TRIS(BENZYLOXY)-2-([TERT-BUTYL(DIMETHYL)SILYL]OXY)CYCLOHEXANOL

Chemical Property:

Purity/Quality:

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Technology Process of 3-(ALLYLOXY)-4,5,6-TRIS(BENZYLOXY)-2-([TERT-BUTYL(DIMETHYL)SILYL]OXY)CYCLOHEXANOL

There total 7 articles about 3-(ALLYLOXY)-4,5,6-TRIS(BENZYLOXY)-2-([TERT-BUTYL(DIMETHYL)SILYL]OXY)CYCLOHEXANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 131146-91-3,131233-71-1,135267-00-4,1214020-75-3
(+/-)-4-O-allyl-1,5,6-tri-O-benzyl-myo-inositol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 136282-33-2
4-O-allyl-1,5,6-tri-O-benzyl-3-O-tert-butyldimethylsilyl-myo-inositol

Guidance literature:: With pyridine; at 50 ℃; for 16h;
DOI:10.1016/S0040-4020(01)86476-0

Reference yield:

: 87-89-8
D-myo-inositol

: 136282-33-2
4-O-allyl-1,5,6-tri-O-benzyl-3-O-tert-butyldimethylsilyl-myo-inositol

Guidance literature:: Multi-step reaction with 7 steps

1: 75 percent / p-toluenesulfonic acid monohydrate / dimethylformamide / 2 h / 95 °C

2: 70 percent / barium oxide, barium hydroxide octahydrate / dimethylformamide / 72 h / 20 °C

3: 1.) NaH / 1.) DMF 2.) 20 degC, 2 h

4: 80 percent / ethylene glycol, p-toluenesulfonic acid monohydrate / CH₂Cl₂ / 2 h / 20 °C

5: 1.) NaH / 1.) DMF, 0 degC 2.) 20 degC, 2 h

6: AcOH, H₂O / 2 h / 95 °C

7: 84 percent / pyridine / 16 h / 50 °C

With pyridine; barium hydroxide octahydrate; water; sodium hydride; toluene-4-sulfonic acid; ethylene glycol; acetic acid; barium(II) oxide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)86476-0

Reference yield:

: 34361-60-9,55123-24-5,55123-26-7,62012-78-6,104873-71-4
1,2:4,5-dicyclohexylidene-myo-inositol

: 136282-33-2
4-O-allyl-1,5,6-tri-O-benzyl-3-O-tert-butyldimethylsilyl-myo-inositol

Guidance literature:: Multi-step reaction with 6 steps

1: 70 percent / barium oxide, barium hydroxide octahydrate / dimethylformamide / 72 h / 20 °C

2: 1.) NaH / 1.) DMF 2.) 20 degC, 2 h

3: 80 percent / ethylene glycol, p-toluenesulfonic acid monohydrate / CH₂Cl₂ / 2 h / 20 °C

4: 1.) NaH / 1.) DMF, 0 degC 2.) 20 degC, 2 h

5: AcOH, H₂O / 2 h / 95 °C

6: 84 percent / pyridine / 16 h / 50 °C

With pyridine; barium hydroxide octahydrate; water; sodium hydride; toluene-4-sulfonic acid; ethylene glycol; acetic acid; barium(II) oxide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)86476-0