N-[oxidophenyl(trifluoromethyl)-λ⁴-sulfanylidene]-acetamide

Base Information

• Chemical Name: N-[oxidophenyl(trifluoromethyl)-λ⁴-sulfanylidene]-acetamide
• CAS No.: 1178899-38-1
• Molecular Formula: C₉H₈F₃NO₂S
• Molecular Weight: 251.229
• Mol file: 1178899-38-1.mol

Synonyms:N-[oxidophenyl(trifluoromethyl)-λ⁴-sulfanylidene]-acetamide

Chemical Property of N-[oxidophenyl(trifluoromethyl)-λ⁴-sulfanylidene]-acetamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-[oxidophenyl(trifluoromethyl)-λ⁴-sulfanylidene]-acetamide

There total 4 articles about N-[oxidophenyl(trifluoromethyl)-λ⁴-sulfanylidene]-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

imino(phenyl)(trifluoromethyl)-λ6-sulfanone (95414-68-9) + acetyl chloride (75-36-5) → N-[oxidophenyl(trifluoromethyl)-λ4-sulfanylidene]-acetamide (1178899-38-1)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; for 5h; Inert atmosphere;

DOI:10.1055/s-0033-1338440

Reference yield: 69.0%

N-acetyl-S-phenyl-S-(trifluoromethyl)sulfilimine (1178899-17-6) → N-[oxidophenyl(trifluoromethyl)-λ4-sulfanylidene]-acetamide (1178899-38-1)

Guidance literature:

With potassium permanganate; water; at 20 ℃;

DOI:10.1002/ejoc.200900410

Reference yield:

phenyl trifluoromethylsulfide (456-56-4) + ammonium carbamate (1111-78-0) → N-[oxidophenyl(trifluoromethyl)-λ4-sulfanylidene]-acetamide (1178899-38-1) + imino(phenyl)(trifluoromethyl)-λ6-sulfanone (95414-68-9)

Guidance literature:

With [bis(acetoxy)iodo]benzene; In 2,2,2-trifluoroethanol; at 20 ℃; for 6h;

DOI:10.1002/chem.201805055

upstream raw materials:

N-acetyl-S-phenyl-S-(trifluoromethyl)sulfilimine

imino(phenyl)(trifluoromethyl)-λ⁶-sulfanone

acetyl chloride

phenyl trifluoromethyl sulfoxide

Downstream raw materials:

oxophenyl(phenylimino)(trifluoromethyl)-λ⁶-sulfane

imino(phenyl)(trifluoromethyl)-λ⁶-sulfanone

N,N-(dimethylamino)-S-phenyl-S-trifluoromethyloxosulfonium trifluoromethanesulfonate