4-Hydroxy-2-(pyridin-4-yl)quinazoline, 4-(4-Hydroxyquinazolin-2-yl)pyridine

Base Information

• Chemical Name: 4-Hydroxy-2-(pyridin-4-yl)quinazoline, 4-(4-Hydroxyquinazolin-2-yl)pyridine
• CAS No.: 6484-23-7
• Molecular Formula: C₁₃H₉N₃O
• Molecular Weight: 223.234
• Hs Code.: 2933599590
• Mol file: 6484-23-7.mol

Synonyms:2-(pyridin-4'-yl)quinazolin-4-(3H)-one

Chemical Property of 4-Hydroxy-2-(pyridin-4-yl)quinazoline, 4-(4-Hydroxyquinazolin-2-yl)pyridine

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

2-(Pyridin-4-yl)quinazolin-4-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Hydroxy-2-(pyridin-4-yl)quinazoline, 4-(4-Hydroxyquinazolin-2-yl)pyridine

There total 4 articles about 4-Hydroxy-2-(pyridin-4-yl)quinazoline, 4-(4-Hydroxyquinazolin-2-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

4-bromopyridin (1120-87-2) + carbon monoxide (201230-82-2) + anthranilic acid amide (28144-70-9,88-68-6) → 2-(pyridin-4'-yl)quinazolin-4-(3H)-one (6484-23-7)

Guidance literature:

With palladium diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; catacxium A; In N,N-dimethyl-formamide; at 120 ℃; for 16h; under 7500.75 Torr; Inert atmosphere; Autoclave;

DOI:10.1002/chem.201302182

Reference yield: 80.0%

4-iodopyridine (15854-87-2) + carbon monoxide (201230-82-2) + anthranilic acid amide (28144-70-9,88-68-6) → 2-(pyridin-4'-yl)quinazolin-4-(3H)-one (6484-23-7)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; at 120 ℃; for 20h; under 7500.75 Torr; Inert atmosphere; Autoclave;

DOI:10.1016/j.jorganchem.2018.09.003

Reference yield: 78.0%

pyridine-4-carbaldehyde (872-85-5) + anthranilic acid amide (28144-70-9,88-68-6) → 2-(pyridin-4'-yl)quinazolin-4-(3H)-one (6484-23-7)

Guidance literature:

In dimethyl sulfoxide; at 100 ℃;

DOI:10.1016/j.bmcl.2017.05.064

upstream raw materials:

4-bromopyridin

carbon monoxide

anthranilic acid amide

pyridine-4-carbaldehyde

Downstream raw materials:

4-chloro-2-(pyridin-4-yl)quinazoline

3-((2-(pyridin-4-yl)quinazolin-4-yl)amino)benzoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 6484-23-7 4-Hydroxy-2-(pyridin-4-yl)quinazoline, 4-(4-Hydroxyquinazolin-2-yl)pyridine

Send

Send

Metric Ton KG G Pound L ML

Send

Send