2-Phenylquinoline-4-carboxylic acid;chloride

Base Information

Chemical Name:2-Phenylquinoline-4-carboxylic acid;chloride
CAS No.:59661-86-8
Molecular Formula:C16H10ClNO
Molecular Weight:267.714
Hs Code.:2933499090
DSSTox Substance ID:DTXSID60700175
Mol file:59661-86-8.mol

Synonyms:DTXSID60700175;2-phenylquinoline-4-carboxylic acid;chloride

Suppliers and Price of 2-Phenylquinoline-4-carboxylic acid;chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
4-QUINOLINECARBONYLCHLORIDE,2-PHENYL- 95
10g
$ 1925.00

Atlantic Research Chemicals
2-Phenylquinoline-4-carbonylchloride 95%
1gm:
$ 307.51

American Custom Chemicals Corporation
2-PHENYLQUINOLINE-4-CARBOXYLIC ACIDCHLORIDE 95.00%
5MG
$ 503.20

Total 6 raw suppliers

Chemical Property of 2-Phenylquinoline-4-carboxylic acid;chloride

Chemical Property:

PSA：29.96000
LogP:4.28080
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:284.0478313
Heavy Atom Count:20
Complexity:325

Purity/Quality:

99%, ^*data from raw suppliers

4-QUINOLINECARBONYLCHLORIDE,2-PHENYL- 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=C2)C(=O)O.[Cl-]

Technology Process of 2-Phenylquinoline-4-carboxylic acid;chloride

There total 9 articles about 2-Phenylquinoline-4-carboxylic acid;chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 132-60-5
cinchophen

: 59661-86-8
2-phenylquinoline-4-carbonyl chloride

Guidance literature:: With thionyl chloride; Erhitzen des Hydrochlorids im Vakuum auf 130grad;

Reference yield:

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 59661-86-8
2-phenylquinoline-4-carbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / ethanol / 80 °C

2: thionyl chloride / 2 h / 80 °C

With thionyl chloride; potassium hydroxide; In ethanol;
DOI:10.1021/jm201207h

Reference yield:

: 98-86-2
acetophenone

: 59661-86-8
2-phenylquinoline-4-carbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: aq. KOH / ethanol / 80 °C

2: (COCl)2 / CH₂Cl₂ / 5 - 20 °C

With potassium hydroxide; oxalyl dichloride; In ethanol; dichloromethane;
DOI:10.1021/jm980633c