4-methyl-trans-4-hexenol tert-butyldiphenylsilyl ether

Base Information

Chemical Name:4-methyl-trans-4-hexenol tert-butyldiphenylsilyl ether
CAS No.:777075-10-2
Molecular Formula:C₂₃H₃₂OSi
Molecular Weight:352.592
Hs Code.:

Synonyms:4-methyl-trans-4-hexenol tert-butyldiphenylsilyl ether

Suppliers and Price of 4-methyl-trans-4-hexenol tert-butyldiphenylsilyl ether

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-methyl-trans-4-hexenol tert-butyldiphenylsilyl ether

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-methyl-trans-4-hexenol tert-butyldiphenylsilyl ether

There total 3 articles about 4-methyl-trans-4-hexenol tert-butyldiphenylsilyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 3017-71-8
(E)-2-bromobut-2-ene

: 177338-13-5
3-(tert-butyldiphenylsilyloxy)propyl bromide

: 777075-10-2
4-methyl-trans-4-hexenol tert-butyldiphenylsilyl ether

Guidance literature:: (E)-2-bromobut-2-ene; With tert.-butyl lithium; at -78 ℃;

3-(tert-butyldiphenylsilyloxy)propyl bromide;
DOI:10.1248/bpb.27.1070

Reference yield: 85.0%

: 13294-71-8
2-bromo-but-2-ene

: C₂₇H₃₉BO₂Si

: 777075-10-2
4-methyl-trans-4-hexenol tert-butyldiphenylsilyl ether

Guidance literature:: 2-bromo-but-2-ene; With potassium phosphate; N,N-diisopropyl 2-dicyclohexylphosphino-4-(2',6'-dimethylphenyl)benzamide; palladium diacetate; In tetrahydrofuran; water; at 20 ℃; for 0.0833333h; Inert atmosphere;

C₂₇H₃₉BO₂Si; In tetrahydrofuran; water; at 20 ℃; for 3h; Inert atmosphere;
DOI:10.1002/ejoc.201201602

Reference yield:

: 114671-83-9
1-(t-butyldiphenylsilyloxy)-3-iodopropane

: 777075-10-2
4-methyl-trans-4-hexenol tert-butyldiphenylsilyl ether

Guidance literature:: Multi-step reaction with 2 steps

1.1: hexane; diethyl ether / 0.08 h / -78 °C / Inert atmosphere

1.2: 0.17 h / -78 °C / Inert atmosphere

1.3: 1.67 h / -78 - 20 °C / Inert atmosphere

2.1: N,N-diisopropyl 2-dicyclohexylphosphino-4-(2',6'-dimethylphenyl)benzamide; palladium diacetate; potassium phosphate / tetrahydrofuran; water / 0.08 h / 20 °C / Inert atmosphere

2.2: 3 h / 20 °C / Inert atmosphere

With potassium phosphate; N,N-diisopropyl 2-dicyclohexylphosphino-4-(2',6'-dimethylphenyl)benzamide; palladium diacetate; In tetrahydrofuran; diethyl ether; hexane; water; 2.1: |Suzuki-Miyaura Coupling / 2.2: |Suzuki-Miyaura Coupling;
DOI:10.1002/ejoc.201201602